Emerging tumor-on-chips with electrochemical biosensors
Cancer, one of the most dangerous diseases with a high mortality rate, has attracted much
attention and interest. Advances in tissue engineering and microfluidics have led to the …
attention and interest. Advances in tissue engineering and microfluidics have led to the …
3D cancer models: One step closer to in vitro human studies
N Manduca, E Maccafeo, R De Maria, A Sistigu… - Frontiers in …, 2023 - frontiersin.org
Cancer immunotherapy is the great breakthrough in cancer treatment as it displayed
prolonged progression-free survival over conventional therapies, yet, to date, in only a …
prolonged progression-free survival over conventional therapies, yet, to date, in only a …
Micro-engineering and nano-engineering approaches to investigate tumour ecosystems
The interactions among tumour cells, the tumour microenvironment (TME) and non-tumour
tissues are of interest to many cancer researchers. Micro-engineering approaches and …
tissues are of interest to many cancer researchers. Micro-engineering approaches and …
Precision biomaterials in cancer theranostics and modelling
Despite significant achievements in the understanding and treatment of cancer, it remains a
major burden. Traditional therapeutic approaches based on the 'one-size-fits-all'paradigm …
major burden. Traditional therapeutic approaches based on the 'one-size-fits-all'paradigm …
[HTML][HTML] Immunocompetent cancer-on-chip models to assess immuno-oncology therapy
TI Maulana, E Kromidas, L Wallstabe… - Advanced Drug Delivery …, 2021 - Elsevier
The advances in cancer immunotherapy come with several obstacles, limiting its
widespread use and benefits so far only to a small subset of patients. One of the underlying …
widespread use and benefits so far only to a small subset of patients. One of the underlying …
Organ‐on‐a‐chip technologies for biomedical research and drug development: A focus on the vasculature
D Soto Veliz, KL Lin, C Sahlgren - Smart medicine, 2023 - Wiley Online Library
Current biomedical models fail to replicate the complexity of human biology. Consequently,
almost 90% of drug candidates fail during clinical trials after decades of research and …
almost 90% of drug candidates fail during clinical trials after decades of research and …
Go with the flow: modeling unique biological flows in engineered in vitro platforms
Interest in recapitulating in vivo phenomena in vitro using organ-on-a-chip technology has
grown rapidly and with it, attention to the types of fluid flow experienced in the body has …
grown rapidly and with it, attention to the types of fluid flow experienced in the body has …
Boosting the clinical translation of organ-on-a-Chip technology
Organ-on-a-chip devices have become a viable option for investigating critical physiological
events and responses; this technology has matured substantially, and many systems have …
events and responses; this technology has matured substantially, and many systems have …
Bio-inspired microfluidics: A review
Biomicrofluidics, a subdomain of microfluidics, has been inspired by several ideas from
nature. However, while the basic inspiration for the same may be drawn from the living …
nature. However, while the basic inspiration for the same may be drawn from the living …
Modeling 3D human tumor lymphatic vessel network using high‐throughput platform
The lymphatic vessel (LV) plays an important role in cancer biology as a major route for
tumor metastasis. Whereas, recent oncoimmunological approaches have focused its role in …
tumor metastasis. Whereas, recent oncoimmunological approaches have focused its role in …