The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Emerging evidence reveal that tumor-associated bacteria (TAB) can facilitate the initiation
and progression of multiple types of cancer. Recent work has emphasized the significant …

The poor prognosis of head and neck cancer (HNC) is associated with metastasis within the
lymph nodes (LNs). Herein, the proteome of 140 multisite samples from a 59-HNC patient …

While altered protein glycosylation is regarded a trait of oral squamous cell carcinoma
(OSCC), the heterogeneous and dynamic glycoproteome of tumor tissues from OSCC …

Salivary gland tumors are highly variable in clinical presentation and histology. The World
Health Organization (WHO) classifies 22 types of malignant and 11 types of benign tumors …

The search for biomarkers associated with oral leukoplakia malignant transformation is
critical for early diagnosis and improved prognosis of oral cancer patients. This systematic …

Diverse proteomics-based strategies have been applied to saliva to quantitatively identify
diagnostic and prognostic targets for oral cancer. Considering that these targets may be …

Introduction: Oral squamous cell carcinoma (OSCC) ranks among the top 10 leading causes
of cancer worldwide, with 5-year survival rate of about 50%, high lymph node metastasis …

Investigating site-specific protein phosphorylation remains a challenging task. The present
study introduces a two-step chemical derivatization method for accurate identification of …

Conventional peptides (CPs) and non-conventional peptides (NCPs) are generated from
small open reading frames, but most CPs are derived from large precursors. NCPs, which …