Inflammation and oxidative stress play major roles in healthy and pathological pregnancy.
Environmental exposure to chemical pollutants may adversely affect maternal and fetal …

Certain limitations exist for animals to modify fatty acid changes. Besides the role of
arachidonic acid (AA), docosahexaenoic acid (DHA) and other 20-carbon long-chain …

Maternal metabolism during pregnancy shapes offspring health via in utero programming. In
the Healthy Start study, we identified five subgroups of pregnant women based on …

Humans are exposed to complex mixtures of phthalates. Gestational exposure to phthalates
has been linked to preeclampsia and preterm birth through potential pathways such as …

Background Exposure to consumer product chemicals during pregnancy may increase
susceptibility to pregnancy disorders by influencing maternal inflammation. However, effects …

Background Inflammation and oxidative stress are critical to pregnancy, but most human
study has focused on downstream, non-causal indicators. Oxylipins are lipid mediators of …

Background: Preterm birth is an important risk factor for neurodevelopmental disabilities.
The vast majority of these disabilities occur, however, among term births. The role of fetal …

The pathways involved in the pathophysiology of fetal growth restriction (FGR) and small for
gestational age (SGA) are incompletely understood. We conduct a systematic review to …

Variants in FDXR reportedly cause autosomal recessive auditory neuropathy and optic
atrophy, expanding to retinal dystrophy. This study aimed to further clarify associated …

Prenatal per-and poly-fluoroalkyl substances (PFAS) exposure may influence gestational
outcomes through bioactive lipids─ metabolic and inflammation pathway indicators. We …