Complex functioning of the genome in the cell nucleus is controlled at different levels:(a) the
DNA base sequence containing all relevant inherited information;(b) epigenetic pathways …

DNA nanotechnology, developing rapidly in recent years, has unprecedented superiorities
in biological application-oriented research including high programmability, convenient …

Background It is becoming clearer that living cells use water/water (w/w) phase separation to
form membraneless organelles that exhibit various important biological functions. Currently …

Hydroxyurea (HU; hydroxycarbamide) is a chemotherapy medication used to treat various
types of cancer and other diseases such as sickle cell anemia. HU inhibits DNA synthesis by …

Polyamines have important roles in the modulation of the cellular function and are
ubiquitous in cells. The polyamines putrescine2+, spermidine3+, and spermine4+ represent …

Alcohols are used in the life sciences because they can condense and precipitate DNA.
Alcohol consumption has been linked to many diseases and can alter genetic activity. In the …

Daunomycin (DM), an anthracycline antibiotic, is frequently used to treat various cancers,
but the direct effects of DM on gene expression and DNA structure are unclear. We used an …

Spermidine is an aliphatic polyamine that directs a set of biological processes. This work
aimed to use UV–Vis spectroscopy, fluorescence spectroscopy, thermal stability, kinetic …

The effect of monovalent cations on a cell‐free transcription–translation (TX–TL) system is
examined using a luciferase assay. It is found that the potency for all ions analyzed here is in …

By adapting the method of single molecular observation for individual DNAs, it will be shown
that reliable analysis of double-strand breaks, DSBs, becomes possible for various kinds of …