The vasa vasorum are a vital microvascular network supporting the outer wall of larger blood
vessels. Although these dynamic microvessels have been studied for centuries, the …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The initial stage
of CVDs is characterized by endothelial dysfunction, defined as the limited bioavailability of …

The miR-200 family plays a crucial role in epithelial to mesenchymal transition via
controlling cell migration and polarity. We hypothesized that miR-200b, one miR-200 family …

As an endocrine disease, type 2 diabetes mellitus (T2DM) can cause testicular damage
which induces male infertility. However, the underlying mechanism is still not clear. We …

An intact microcirculation is vital for diffusion of oxygen and nutrients and for removal of
toxins of every organ and system in the human body. The functional and/or anatomical loss …

Metabolic impairments in maternal obesity and gestational diabetes mellitus (GDM) induce
an abnormal environment in peripheral blood and cause vascular structure alterations which …

Tumor growth depends on angiogenesis and inducing angiogenesis is one of the most
important hallmarks in the cancer development. Treatment with small molecules that inhibit …

Key points Maternal hypoxia is a common perturbation that may impair fetal development
and programme sex specific disease outcomes in offspring. There is growing interest in the …

Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is
essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid …

Biodegradable magnesium (Mg) metals have been applied in orthopaedic and stent
applications due to their biodegradability, bioabsorbability and adaptability to tissue …