Functional properties of grape and wine polyphenols

G Giovinazzo, F Grieco - Plant foods for human nutrition, 2015 - Springer
Grape berries polyphenols are mainly synthesized in the skin tissues and seeds and they
are extracted during the winemaking process. These substances have a potentially positive …

[HTML][HTML] Diet regulation of long-chain PUFA synthesis: role of macronutrients, micronutrients, and polyphenols on Δ-5/Δ-6 desaturases and elongases 2/5

M Gonzalez-Soto, DM Mutch - Advances in Nutrition, 2021 - Elsevier
Deficiencies in the n–3 (ω-3) long-chain PUFAs (LC-PUFAs) EPA and DHA are associated
with increased risk for the development of numerous diseases. Although n–3 LC-PUFAs can …

Citrus flavanones naringenin and hesperetin improve antioxidant status and membrane lipid compositions in the liver of old-aged Wistar rats

M Miler, J Živanović, V Ajdžanović… - Experimental …, 2016 - Elsevier
This study aimed to investigate effects of citrus flavanones naringenin (NAR) and hesperetin
(HES) on liver antioxidant status and membrane phospholipid composition in 24-month-old …

Is cytotoxicity a determinant of the different in vitro and in vivo effects of bioactives?

M Di Nunzio, V Valli, L Tomás-Cobos… - … and alternative medicine, 2017 - Springer
Background Foodstuffs of both plant and animal origin contain a wide range of bioactive
compounds. Although human intervention studies are mandatory to assess the health effects …

Faecal metabolomic fingerprint after moderate consumption of red wine by healthy subjects

A Jimenez-Giron, C Ibáñez, A Cifuentes… - Journal of proteome …, 2015 - ACS Publications
Faecal metabolome contains information on the metabolites found in the intestine, from
which knowledge about the metabolic function of the gut microbiota can be obtained …

Perilla frutescens seed oil combined with Anredera cordifolia leaf powder attenuates age-related cognitive decline by reducing serum triglyceride and glucose levels …

M Hashimoto, K Matsuzaki, K Maruyama… - Food & function, 2022 - pubs.rsc.org
We have shown that Anredera cordifolia extract improves learning and memory in a
senescence-accelerated mouse model, and that α-linolenic acid (ALA)-rich Perilla …

Malvidin 3‐Glucoside Modulated Gut Microbial Dysbiosis and Global Metabolome Disrupted in a Murine Colitis Model Induced by Dextran Sulfate Sodium

F Liu, TTY Wang, Q Tang, C Xue… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope This study aims to elucidate the mechanisms of the anthocyanin malvidin 3‐
glucoside (MV) in alleviating gut dysbiosis using a murine colitis model induced by dextran …

[HTML][HTML] n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD

D Vauzour, I Rodriguez-Ramiro, S Rushbrook… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults and at present no licensed
medication has been approved. Despite its complex patho-physiology, dietary strategies …

Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men

S McManus, N Tejera, K Awwad, D Vauzour… - Journal of lipid …, 2016 - ASBMB
Our objective was to investigate the impact of EPA versus DHA on arterial stiffness and
reactivity and underlying mechanisms (with a focus on plasma oxylipins) in the postprandial …

[HTML][HTML] A transgenic Camelina sativa seed oil effectively replaces fish oil as a dietary source of eicosapentaenoic acid in mice

N Tejera, D Vauzour, MB Betancor, O Sayanova… - The Journal of …, 2016 - Elsevier
Background: Fish currently supplies only 40% of the eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) required to allow all individuals globally to meet the minimum …