Sequence analysis of complex amplicons

M Faham, M Moorhead, T Willis - US Patent 9,523,129, 2016 - Google Patents
US Appl. No. 14/404,435, filed Nov. 26, 2014, Faham et al. Bertness, et al. T-cell receptor
gene rearrangements as clinical (60) Provisional application No. 61/112,693, filed on Nov …

Methods of monitoring conditions by sequence analysis

M Faham, T Willis - US Patent 10,246,752, 2019 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
42153463&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Random array sequencing of low-complexity libraries

J Zheng, T Willis, M Faham - US Patent 10,385,475, 2019 - Google Patents
The invention is directed to a method of sequencing low-complexity amplicons randomly
arrayed at high density on a surface. Methods of the invention include preparing amplicons …

Monitoring health and disease status using clonotype profiles

M Faham, T Willis - US Patent 9,512,487, 2016 - Google Patents
2022-09-15 Assigned to ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP
reassignment ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP SECURITY …

Method for generating clonotype profiles using sequence tags

T Asbury, K Hervold, C Kotwaliwale, M Faham… - US Patent …, 2017 - Google Patents
US9708657B2 - Method for generating clonotype profiles using sequence tags - Google
Patents US9708657B2 - Method for generating clonotype profiles using sequence tags …

Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions

HS Robins, CS Carlson, RJ Livingston… - US Patent …, 2016 - Google Patents
2015-03-19 Assigned to ADAPTIVE BIOTECHNOLOGIES CORPORATION reassignment
ADAPTIVE BIOTECHNOLOGIES CORPORATION ASSIGNMENT OF ASSIGNORS …

Method of sequence determination using sequence tags

M Faham, M Moorhead, T Willis, J Zheng - US Patent 9,506,119, 2016 - Google Patents
The invention is directed to the use of sequence tags to improve sequence determination of
amplicons of related sequences, particularly large and complex amplicons, such as those …

Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia

F Pepin, V Carlton, M Klinger, M Faham - US Patent 9,365,901, 2016 - Google Patents
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Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization

HS Robins, J Rubinstein, R Emerson… - US Patent 10,221,461, 2019 - Google Patents
Disclosed are methods for determining the immunological status of the adaptive immune
system of a subject by identifying and quantifying rearranged DNA (and/or subse quently …

Quantification of adaptive immune cell genomes in a complex mixture of cells

HS Robins, RJ Livingston, JH Bielas - US Patent 9,279,159, 2016 - Google Patents
2022-12-22 Assigned to FRED HUTCHINSON CANCER CENTER reassignment FRED
HUTCHINSON CANCER CENTER MERGER AND CHANGE OF NAME (SEE DOCUMENT …