Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

In the era of functional genomics, the need for tools to perform large-scale targeted and
random mutagenesis is increasing. A potential tool is Agrobacterium-mediated fungal …

The fungus Cryptococcus neoformans is a leading cause of mortality and morbidity among
HIV-infected individuals. We utilized the completed genome sequence and optimized …

Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

Light inhibits mating and haploid fruiting of the human fungal pathogen Cryptococcus
neoformans, but the mechanisms involved were unknown. Two genes controlling light …

The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Many transformation methods have been developed to introduce DNA into filamentous
fungi. One of these methods is Agrobacterium-mediated transformation (AMT). Here, we …

The ability to produce melanin is a key virulence factor in many fungal pathogens including
the human basidiomycete pathogen Cryptococcus neoformans, a major cause of life …

Nitric oxide has attracted considerable interest from plant pathologists due its established
role in regulating mammalian anti-microbial defences, particularly via programmed cell …