Since the first cases of AIDS appeared in 1981, human immunodeficiency virus type 1 (HIV-
1) infection has reached pandemic proportions. Forty years later, research has led to the …

The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …

Modern drug delivery technology began in 1952 with the advent of the Spansule® sustained-
release capsule technology, which can deliver a drug for 12 h after oral administration …

The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

Ultra-long-acting integrase strand transfer inhibitors were created by screening a library of
monomeric and dimeric dolutegravir (DTG) prodrug nanoformulations. This led to an 18 …

Introduction Poor or inconsistent adherence to daily oral pre-exposure prophylaxis (PrEP)
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …

Emerging cancer cases across the globe and treating them with conventional therapies with
multiple limitations have been challenging for decades. Novel drug delivery systems and …

Worldwide, women face compounding reproductive health risks, including human
immunodeficiency virus (HIV), sexually-transmitted infections (STIs), and unintended …

Vaccines and antivirals are the classical weapons deployed to contain, prevent, and treat life-
threatening viral illnesses. Specifically, for SARS-CoV-2 infection, vaccines protect against …

Introduction Controlled/extended-release formulations offer numerous benefits over
conventional especially reduced side effects, improved therapeutic outcomes, and high …