A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Self-driving laboratories for chemistry and materials science

G Tom, SP Schmid, SG Baird, Y Cao, K Darvish… - Chemical …, 2024 - ACS Publications
Self-driving laboratories (SDLs) promise an accelerated application of the scientific method.
Through the automation of experimental workflows, along with autonomous experimental …

Predicting transcriptional outcomes of novel multigene perturbations with GEARS

Y Roohani, K Huang, J Leskovec - Nature Biotechnology, 2024 - nature.com
Understanding cellular responses to genetic perturbation is central to numerous biomedical
applications, from identifying genetic interactions involved in cancer to developing methods …

A multi-organ chip with matured tissue niches linked by vascular flow

K Ronaldson-Bouchard, D Teles, K Yeager… - Nature Biomedical …, 2022 - nature.com
Engineered tissues can be used to model human pathophysiology and test the efficacy and
safety of drugs. Yet, to model whole-body physiology and systemic diseases, engineered …

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

L Ewart, A Apostolou, SA Briggs, CV Carman… - Communications …, 2022 - nature.com
Background Conventional preclinical models often miss drug toxicities, meaning the harm
these drugs pose to humans is only realized in clinical trials or when they make it to market …

Human organoids in basic research and clinical applications

XY Tang, S Wu, D Wang, C Chu, Y Hong… - Signal transduction and …, 2022 - nature.com
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …

[图书][B] Ethics and governance of artificial intelligence for health: WHO guidance: executive summary

World Health Organization - 2021 - apps.who.int
Искусственным интеллектом (ИИ) называют способность алгоритмов, закодированных
в технологии, обучаться на основе данных, чтобы они могли выполнять …

An outlook on microfluidics: the promise and the challenge

S Battat, DA Weitz, GM Whitesides - Lab on a Chip, 2022 - pubs.rsc.org
This perspective considers ways in which the field of microfluidics can increase its impact by
improving existing technologies and enabling new functionalities. We highlight applications …

Towards in vitro models for reducing or replacing the use of animals in drug testing

DM Stresser, AK Kopec, P Hewitt… - Nature Biomedical …, 2024 - nature.com
Towards in vitro models for reducing or replacing the use of animals in drug testing | Nature
Biomedical Engineering Skip to main content Thank you for visiting nature.com. You are using …