Inflammation, lifestyle factors, and the microbiome‐gut‐brain Axis: relevance to depression and antidepressant action

F Donoso, JF Cryan… - Clinical …, 2023 - Wiley Online Library
Depression is considered a major public health concern, where existing pharmacological
treatments are not equally effective across all patients. The pathogenesis of depression …

Recipient factors in faecal microbiota transplantation: one stool does not fit all

C Danne, N Rolhion, H Sokol - Nature Reviews Gastroenterology & …, 2021 - nature.com
Faecal microbiota transplantation (FMT) is a promising therapy for chronic diseases
associated with gut microbiota alterations. FMT cures 90% of recurrent Clostridioides difficile …

Fecal microbiota transplantation reduces symptoms in some patients with irritable bowel syndrome with predominant abdominal bloating: short-and long-term results …

T Holvoet, M Joossens, JF Vázquez-Castellanos… - Gastroenterology, 2021 - Elsevier
Background & Aims Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder
associated with intestinal dysbiosis. Given the reported promising results of open-label fecal …

Fecal microbiota transplantation (FMT) as an adjunctive therapy for depression—case report

JPK Doll, JF Vázquez-Castellanos, AC Schaub… - Frontiers in …, 2022 - frontiersin.org
Depression is a debilitating disorder, and at least one third of patients do not respond to
therapy. Associations between gut microbiota and depression have been observed in recent …

Fecal microbiota transplantation as new therapeutic avenue for human diseases

M Biazzo, G Deidda - Journal of Clinical Medicine, 2022 - mdpi.com
The human body is home to a variety of micro-organisms. Most of these microbial
communities reside in the gut and are referred to as gut microbiota. Over the last decades …

Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome

AL Edwinson, L Yang, S Peters, N Hanning… - Nature …, 2022 - nature.com
Intestinal proteases mediate digestion and immune signalling, while increased gut
proteolytic activity disrupts the intestinal barrier and generates visceral hypersensitivity …

Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection

A Yadegar, S Pakpoor, FF Ibrahim, A Nabavi-Rad… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent
Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical …

Roles of the gut virome and mycobiome in faecal microbiota transplantation

S Lam, X Bai, AN Shkoporov, H Park, X Wu… - The Lancet …, 2022 - thelancet.com
Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are
associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with …

[HTML][HTML] Gut bless you: The microbiota-gut-brain axis in irritable bowel syndrome

EMR Hillestad, A van der Meeren… - World journal of …, 2022 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a common clinical label for medically unexplained
gastrointestinal symptoms, recently described as a disturbance of the microbiota-gut-brain …

Phages and their potential to modulate the microbiome and immunity

S Federici, SP Nobs, E Elinav - Cellular & molecular immunology, 2021 - nature.com
Bacteriophages (hence termed phages) are viruses that target bacteria and have long been
considered as potential future treatments against antibiotic-resistant bacterial infection …