Paclitaxel in colon cancer management: from conventional chemotherapy to advanced nanocarrier delivery systems
Komal, BP Nanda, L Singh, R Bhatia… - … Archives of Pharmacology, 2024 - Springer
Paclitaxel, a potent chemotherapeutic agent derived from the bark of the Pacific yew tree,
has demonstrated significant efficacy in the treatment of various cancers, including colon …
has demonstrated significant efficacy in the treatment of various cancers, including colon …
Spatiotemporal release of non-nucleotide STING agonist and AKT inhibitor from implantable 3D-printed scaffold for amplified cancer immunotherapy
H Wang, Z Liu, Y Fang, X Luo, C Zheng, Y Xu, X Zhou… - Biomaterials, 2024 - Elsevier
Immunotherapy through the activation of the stimulator of interferon genes (STING) signaling
pathway is increasingly recognized for its robust anti-tumor efficacy. However, the …
pathway is increasingly recognized for its robust anti-tumor efficacy. However, the …
Design and synthesis of cyclic dinucleotide analogues containing triazolyl C-nucleosides
J Ma, H Xu, K Hou, Y Cao, D Xie, J Yan… - The Journal of …, 2024 - ACS Publications
Natural cyclic dinucleotide (CDN) is the secondary messenger involved in bacterial
hemostasis, human innate immunity, and bacterial antiphage immunity. Synthetic CDN and …
hemostasis, human innate immunity, and bacterial antiphage immunity. Synthetic CDN and …
Tumor-responsive covalent organic polymeric nanoparticles enhancing STING activation for cancer immunotherapy
S Liang, J Yao, D Liu, M Zhou, Y Cui, Z Wang - Chinese Chemical Letters, 2024 - Elsevier
The cyclic guanosine monophosphate-adenosine monophosphate synthase and the
stimulator of interferon genes (cGAS-STING) has emerged as a promising target for cancer …
stimulator of interferon genes (cGAS-STING) has emerged as a promising target for cancer …
[HTML][HTML] IDI1 inhibits the cGAS-Sting signaling pathway in hepatocellular carcinoma
L Fu, H Ding, Y Bai, L Cheng, S Hu, Q Guo - Heliyon, 2024 - cell.com
Metabolic reprogramming is one of the prominent features that distinguishes tumor cells
from normal cells. The role of metabolic abnormalities in regulating innate immunity is poorly …
from normal cells. The role of metabolic abnormalities in regulating innate immunity is poorly …