Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Laser ablation–inductively coupled plasma–mass spectrometry imaging in biology

PA Doble, RG de Vega, DP Bishop, DJ Hare… - Chemical …, 2021 - ACS Publications
Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI

MK Andersen, TS Høiem, BSR Claes, B Balluff… - Cancer & …, 2021 - Springer
Background Prostate cancer tissues are inherently heterogeneous, which presents a
challenge for metabolic profiling using traditional bulk analysis methods that produce an …

Recent applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for biological sample analysis: a follow-up review

D Pozebon, GL Scheffler, VL Dressler - Journal of Analytical Atomic …, 2017 - pubs.rsc.org
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a feasible
technique to obtain either quantitative elemental data or spatially resolved imaging/mapping …

Overcoming spectral overlap via inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS). A tutorial review

E Bolea-Fernandez, L Balcaen, M Resano… - Journal of Analytical …, 2017 - pubs.rsc.org
This work reviews the operating principles of ICP-tandem mass spectrometry (ICP-MS/MS)
and the key applications reported on since the introduction of the technique in 2012. The …

Analytical methods for imaging metals in biology: from transition metal metabolism to transition metal signaling

CM Ackerman, S Lee, CJ Chang - Analytical chemistry, 2017 - ACS Publications
Metal elements represent some of the most fundamental chemical building blocks of life and
are required to sustain the growth, development, and sustenance of all living organisms and …

Facets of ICP-MS and their potential in the medical sciences—Part 1: fundamentals, stand-alone and hyphenated techniques

D Clases, R Gonzalez de Vega - Analytical and Bioanalytical Chemistry, 2022 - Springer
Since its inception in the early 80s, inductively coupled plasma–mass spectrometry has
developed to the method of choice for the analysis of elements in complex biological …

Solid sampling: advantages and challenges for chemical element determination—a critical review

RC Machado, DF Andrade, DV Babos… - Journal of Analytical …, 2020 - pubs.rsc.org
In recent decades, direct solid sample analysis has been reported in the literature as an
alternative to traditional methods of sample preparation, becoming well established in the …

Characterisation of microplastics and unicellular algae in seawater by targeting carbon via single particle and single cell ICP-MS

RG de Vega, S Goyen, TE Lockwood, PA Doble… - Analytica Chimica …, 2021 - Elsevier
The discharge of plastic waste and subsequent formation and global distribution of
microplastics (MPs) has caused great concern and highlighted the need for dedicated …

Strategies to enhance figures of merit in ICP-ToF-MS

TE Lockwood, RG De Vega, Z Du, L Schlatt… - Journal of Analytical …, 2024 - pubs.rsc.org
Inductively coupled plasma with time-of-flight mass spectrometry (ICP-ToF-MS) is currently
setting new benchmarks for the analysis of single particles (SP) and elemental mapping …