Bacteriophages in natural and artificial environments
S Batinovic, F Wassef, SA Knowler, DTF Rice… - Pathogens, 2019 - mdpi.com
Bacteriophages (phages) are biological entities that have attracted a great deal of attention
in recent years. They have been reported as the most abundant biological entities on the …
in recent years. They have been reported as the most abundant biological entities on the …
Factors determining phage stability/activity: challenges in practical phage application
E Jończyk-Matysiak, N Łodej, D Kula… - Expert review of anti …, 2019 - Taylor & Francis
Introduction: Phages consist of nucleic acids and proteins that may lose their activity under
different physico-chemical conditions. The production process of phage formulations may …
different physico-chemical conditions. The production process of phage formulations may …
DNA packaging by the double-stranded DNA bacteriophages
WC Earnshaw, SR Casjens - Cell, 1980 - Elsevier
Since the study of the molecular nature of the life cycle of double-stranded DNA
bacteriophages began, the problem of how the chromosome is condensed into the virion …
bacteriophages began, the problem of how the chromosome is condensed into the virion …
Bacteriophage T3 and bacteriophage T7 virus-host cell interactions
DH Krüger, C Schroeder - Microbiological reviews, 1981 - Am Soc Microbiol
The recognition in the 1940s that bacterio-tems. The study of bacteriophages has contrib-
phages could help to elucidate the molecular uted much to the science ofvirology, since …
phages could help to elucidate the molecular uted much to the science ofvirology, since …
Phage-mediated counting by the naked eye of miRNA molecules at attomolar concentrations in a Petri dish
X Zhou, P Cao, Y Zhu, W Lu, N Gu, C Mao - Nature materials, 2015 - nature.com
The ability to count biomolecules such as cancer-biomarker miRNAs with the naked eye is
seemingly impossible in molecular diagnostics. Here, we show an ultrasensitive naked-eye …
seemingly impossible in molecular diagnostics. Here, we show an ultrasensitive naked-eye …
[HTML][HTML] Maturation dynamics of a viral capsid: visualization of transitional intermediate states
R Lata, JF Conway, N Cheng, RL Duda, RW Hendrix… - Cell, 2000 - cell.com
Typical of DNA bacteriophages and herpesviruses, HK97 assembles in two stages:
polymerization and maturation. First, capsid protein polymerizes into closed shells; then …
polymerization and maturation. First, capsid protein polymerizes into closed shells; then …
Bacteriophage P22 portal protein is part of the gauge that regulates packing density of intravirion DNA
S Casjens, E Wyckoff, M Hayden, L Sampson… - Journal of molecular …, 1992 - Elsevier
The complex double-stranded DNA bacteriophages assemble DNA-free protein shells
(procapsids) that subsequently package DNA. In the case of several double-stranded DNA …
(procapsids) that subsequently package DNA. In the case of several double-stranded DNA …
Semi-solid and solid dosage forms for the delivery of phage therapy to epithelia
The delivery of phages to epithelial surfaces for therapeutic outcomes is a realistic proposal,
and indeed one which is being currently tested in clinical trials. This paper reviews some of …
and indeed one which is being currently tested in clinical trials. This paper reviews some of …
Conformational transformations in the protein lattice of phage P22 procapsids
ML Galisteo, J King - Biophysical journal, 1993 - cell.com
During the packaging of double-stranded DNA by bacterial viruses, the precursor procapsid
loses its internal core of scaffolding protein and undergoes a substantial expansion to form …
loses its internal core of scaffolding protein and undergoes a substantial expansion to form …