[HTML][HTML] Microcrystalline cellulose, a direct compression binder in a quality by design environment—A review

G Thoorens, F Krier, B Leclercq, B Carlin… - International journal of …, 2014 - Elsevier
The ICH quality vision introduced the concept of quality by design (QbD), which requires a
greater understanding of the raw material attributes, of process parameters, of their …

Microcrystalline cellulose as pharmaceutical excipient

AY Chaerunisaa, S Sriwidodo… - … design-recent practices, 2019 - books.google.com
Microcrystalline cellulose (MCC) is a pure partially depolymerized cellulose synthesized
from α-cellulose precursor (type Iβ), obtained as a pulp from fibrous plant material, with …

Effect of Particle Size and Pressure on the Transport Properties of the Fast Ion Conductor t‐Li7SiPS8

C Schneider, CP Schmidt, A Neumann… - Advanced Energy …, 2023 - Wiley Online Library
All‐solid‐state batteries promise higher energy and power densities as well as increased
safety compared to lithium‐ion batteries by using non‐flammable solid electrolytes and …

Effect of particle size on powder compaction and tablet strength using limestone

R Cabiscol, H Shi, I Wünsch, V Magnanimo… - Advanced Powder …, 2020 - Elsevier
Processability of powders in high load compaction constitutes a challenge due to particle
rearrangement, compression and breakage occurring simultaneously. Although tableting is …

Spherical agglomerates of lactose with enhanced mechanical properties

D Lamešić, O Planinšek, Z Lavrič, I Ilić - International journal of …, 2017 - Elsevier
The aim of this study was to prepare spherical agglomerates of lactose and to evaluate their
physicochemical properties, flow properties, particle friability and compaction properties …

Effects of moisture content and compression pressure of various deforming granules on the physical properties of tablets

P Thapa, AR Lee, DH Choi, SH Jeong - Powder technology, 2017 - Elsevier
The main purpose of this study was to investigate the effects of moisture content (MC) of
different deformation granules (brittle, plastic, and elastic) and compression pressure (CP) …

Multivariate data analysis to evaluate commonly used compression descriptors

S Berkenkemper, S Klinken, P Kleinebudde - International Journal of …, 2023 - Elsevier
Numerous studies elucidated material behavior based on compression analyses. Especially
compressibility, compactibility and tabletability were in the focus of these investigations. In …

Insight into tableted pellets by combining X-ray micro-computed tomography and experimental compaction

I Boudina, E Rondet, S Nezamabadi, T Sharkawi - Powder Technology, 2022 - Elsevier
Pellets are spherical agglomerated particles used to produce multiparticulate
pharmaceutical dosage forms. This study aims to develop a new approach that evaluates …

Scaling tableting processes from compaction simulator to rotary presses—Mind the sub-processes

I Wünsch, I Friesen, D Puckhaber, T Schlegel, JH Finke - Pharmaceutics, 2020 - mdpi.com
Compaction simulators are frequently used in the formulation and process development of
tablets, bringing about the advantages of flexibility, low material consumption, and high …

Impact of lubrication on key properties of orodispersible minitablets in comparison to conventionally sized orodispersible tablets

J Kuck, J Breitkreutz - European Journal of Pharmaceutics and …, 2022 - Elsevier
Orodispersible minitablets (ODMTs) offer several benefits like easy swallowability, dose
flexibility and simple manufacturing through direct compression. In this study, the effect of …