Diabetes mellitus (DM) is considered as a main challenge in both developing and
developed countries, as lifestyle has changed and its management seems to be vital. Type I …

Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …

Osteoarthritis (OA), characterized by chondrocyte apoptosis and disturbance of the balance
between catabolism and anabolism of the extracellular matrix (ECM), is the most common …

The production of metrnl, a novel adipomyokine, is induced upon exercise in adipose tissue
and skeletal muscle. In this study, we investigated the anti-inflammatory and antipyroptotic …

Myokines are muscle‐derived cytokines and chemokines that act extensively on organs and
exert beneficial metabolic functions in the whole‐body through specific signal networks …

Complex multicellular organisms require a coordinated response from multiple tissues to
maintain whole-body homeostasis in the face of energetic stressors such as fasting, cold …

Exercise is a well-known non-pharmacological intervention to improve brain functions,
including cognition, memory, and motor coordination. Contraction of skeletal muscles during …

Myokines are molecules produced and secreted by skeletal muscle to act in an auto‐, para‐
and endocrine manner to alter physiological function of target tissues. The growing number …

Obesity is associated with chronic low-grade inflammation. The benefits of exercise are
partly attributed to its anti-inflammatory effect, but whether exercise can regulate NLRP3 …

Sarcopenic obesity (SO) is a condition characterized by the occurrence of both sarcopenia
and obesity and imposes a heavy burden on the health of the elderly. Controversies and …