Corneal blindness is a major cause of blindness in the world and corneal transplantation is
the only widely accepted treatment to restore sight in these eyes. However, it is becoming …

The search for alternatives to allotransplants is driven by the shortage of corneal donors and
is demanding because of the limitations of the alternatives. Indeed, current progress in …

The advancement and improvement in decellularization methods can be attributed to the
increasing demand for tissues and organs for transplantation. Decellularized tissues and …

Corneal transplantation remains the ultimate treatment option for advanced stromal and
endothelial disorders. Corneal tissue engineering has gained increasing interest in recent …

Corneal transplantation is the only option to cure corneal opacities. However, there is an
imbalance between supply and demand of corneal tissues in the world. To solve the …

Different approaches have investigated the effects of different extracellular matrices (ECMs)
and three-dimensional (3D) culture on islet function, showing encouraging results. Ideally …

Stromal keratophakia was first performed by José Ignacio Barraquer in the 1960s. The
refractive lamellar keratoplasty technique was intensely pursued in the 1980s as a method …

Decellularization is the process of removal of native cells from tissue, leaving behind a three-
dimensional (3D) ultrastructure of extracellular matrix (ECM) proteins while preserving the …

To address the shortcomings associated with corneal transplants, substantial efforts have
been focused on developing new modalities such as xenotransplantion. Xenogeneic …

Nowadays, the high incidence of peripheral nerve injuries and the low success ratio of
surgical treatments are driving research to the generation of novel alternatives to repair …