In this review, we attempt to give a concise overview of recent progress made in mechanistic
understanding of protein aggregation, particulate formation and protein solution rheology …

Neurodegenerative diseases are a set of progressive and currently incurable diseases that
are primarily caused by neuron degeneration. Neurodegenerative diseases often lead to …

As the physicochemical properties of drug delivery systems are governed not only by the
material properties which they are compose of but by their size that they conform, it is crucial …

As interest in the role of extracellular vesicles in cell-to-cell communication has increased,
so has the use of microscopy and analytical techniques to assess their formation, release …

α-Synuclein is an intrinsically disordered protein abundant in presynaptic terminals in
neurons and in synaptic vesicles. α-Synuclein's interaction with lipid bilayers is important not …

Biological nanoparticles (BNPs) are of high interest due to their key role in various biological
processes and use as biomarkers. BNP size and composition are decisive for their functions …

Exosomes are naturally occurring nanosized particles that aid intercellular communication
by transmitting biological information between cells. Exosomes have therapeutic efficacy …

In the past, analysis of micron-sized (> 1.0 μm) aggregates of therapeutic proteins has been
limited to light obscuration (LO), and appropriate quantitative methods of evaluating protein …

Sample complexity and polydispersity presents challenges surrounding particle size
measurements for nanoparticles (NPs). To ensure the delivery of high quality products to the …

Nanoparticle tracking analysis (NTA) is an important technique for measuring hydrodynamic
size of globular biological particles including liposomes and viruses. Less attention has …