The state of the brain and body constantly varies on rapid and slow timescales. These
variations contribute to the apparent noisiness of sensory responses at both the neural and …

Since the introduction of calcium imaging to monitor neuronal activity with single-cell
resolution, optical imaging methods have revolutionized neuroscience by enabling …

Advanced imaging methods now allow cell-type-specific recording of neural activity across
the mammalian brain, potentially enabling the exploration of how brain-wide dynamical …

The mystery of general anesthesia is that it specifically suppresses consciousness by
disrupting feedback signaling in the brain, even when feedforward signaling and basic …

The successful planning and execution of adaptive behaviors in mammals may require long-
range coordination of neural networks throughout cerebral cortex. The neuronal …

Neural activity throughout the cortex is correlated with perceptual decisions, but inactivation
studies suggest that only a small number of areas are necessary for these behaviors. Here …

Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

Perceptual decisions involve distributed cortical activity. Does information flow sequentially
from one cortical area to another, or do networks of interconnected areas contribute at the …

Traditionally studies of brain function have focused on task-evoked responses. By their very
nature such experiments tacitly encourage a reflexive view of brain function. While such an …

Summary Ultra-slow,∼ 0.1-Hz variations in the oxygenation level of brain blood are widely
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …