Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population

AS Zahedi, M Zarkesh, B Sedaghati-khayat… - Journal of Diabetes & …, 2023 - Springer
Background Specific biomarkers for metabolic syndrome (MetS) may improve diagnostic
specificity for clinical information. One of the main pathophysiological mechanisms of MetS …

Combined Network Pharmacology and Molecular Docking to Verify the Treatment of Type 2 Diabetes with Pueraria Lobata Radix and Salviae Miltiorrhizae Radix

J Mao, G Wang, L Yang, L Tan, C Tian… - … Methods in Medicine, 2023 - Wiley Online Library
Objective. To explore the potential molecular mechanism of Pueraria Lobata Radix (RP) and
Salviae Miltiorrhizae Radix (RS) in the treatment of type 2 diabetes mellitus (T2DM) based …

Genetically engineered exosomes as a potential regulator of Th1 cells response in rheumatoid arthritis

Z Ren, X Liu, E Abdollahi… - Biopreservation and …, 2023 - liebertpub.com
Background: Rheumatoid arthritis is a long-lasting inflammatory disease that usually
involves joints, but it can also affect other organs, including the skin and lungs. In this case, it …

A Network Pharmacology to Explore the Mechanism of Calculus Bovis in the Treatment of Ischemic Stroke

F Liu, L Li, J Chen, Y Wu, Y Cao… - BioMed Research …, 2021 - Wiley Online Library
Background. Calculus Bovis is a valuable Chinese medicine, which is widely used in the
clinical treatment of ischemic stroke. The present study is aimed at investigating its target …

Association between obesity categories with cardiovascular disease and its related risk factors in the MASHAD cohort study population

H Ghazizadeh, SMR Mirinezhad… - Journal of Clinical …, 2020 - Wiley Online Library
Background Cardiovascular disease (CVD) is a significant cause of morbidity and mortality
globally. Obesity is an important CVD risk factor and is increasing in prevalence. Methods In …

Genetic Variations of AKT1 are Associated with Risk Screening for Non-Alcoholic Fatty Liver Disease

Y Ding, Z Tang, R Zhang, M Zhang… - … and Healthcare Policy, 2023 - Taylor & Francis
Purpose Protein kinase B (PKB/AKT) has shown a high profile in the research of metabolic
diseases. This research sought to determine whether the AKT1 gene's single nucleotide …

[HTML][HTML] In Silico Investigation of AKT2 Gene and Protein Abnormalities Reveals Potential Association with Insulin Resistance and Type 2 Diabetes

ME Elangeeb, I Elfaki, MA Elkhalifa, KM Adam… - Current Issues in …, 2023 - mdpi.com
Type 2 diabetes (T2D) develops from insulin resistance (IR) and the dysfunction of
pancreatic beta cells. The AKT2 protein is very important for the protein signaling pathway …

[HTML][HTML] Association and functional study between ADIPOQ and metabolic syndrome in elderly Chinese Han population

Q Wang, D Ren, Y Bi, R Yuan, D Li, J Wang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Objective: Metabolic syndrome (MetS) is a cluster of health problems that places individuals
at higher risk of developing cardiovascular disease, diabetes and stroke. The prevalence of …

[HTML][HTML] Exploring the Potential Lipid-Lowering and Weight-Reducing Mechanisms of FH06 Fermented Beverages Based on Non-Targeted Metabolomics and …

H Wang, T Wang, J Wang, R Liu, Y Cui, X Wu, R Dai… - Fermentation, 2024 - mdpi.com
Investigating the intricate pathways through which FH06 fermentation broth exerts lipid-
lowering and weight-loss effects is pivotal for advancing our comprehension of metabolic …

[PDF][PDF] PI3K/AKT 通路在动物葡萄糖代谢中的研究进展

孙冠聪, 焦丹, 谢忠奎, 周平, 杨果 - 生命科学, 2021 - lifescience.sinh.ac.cn
葡萄糖代谢稳态对维持动物健康水平至关重要. 磷脂酰肌醇3-激酶(phosphoinositide 3-kinase,
PI3K) 是受体酪氨酸激酶(receptor tyrosine kinase, RTK) 和G 蛋白偶联受体(G protein-coupled …