The incidence of necrotising soft-tissue infections has increased during recent decades such
that most physicians might see at least one case of these potentially life-threatening …

Necrotizing soft tissue infections (NSTIs) are rare life-threatening bacterial infections
characterized by an extensive necrosis of skin and subcutaneous tissues. Initial urgent …

Variability in disease severity caused by a microbial pathogen is impacted by each infection
representing a unique combination of host and pathogen genomes. Here, we show that the …

Background Necrotizing soft-tissue infections (NSTI) are life-threatening conditions often
caused by β-hemolytic streptococci, group A Streptococcus (GAS) in particular. Optimal …

Sepsis is a biphasic disease characterized by an acute inflammatory response, followed by
a prolonged immunosuppressive phase. Therapies aimed at controlling inflammation help to …

Variants of SARS-CoV-2 have emerged that are more transmissible than the original virus or
that exhibit some properties of immune escape, or both. The beta (B. 1.351) variant has …

The 28th edition of Bailey & Love's Short Practice of Surgery is the leading surgical resource
for medical students and surgeons in training. It encompasses the basic principles of careful …

Objective To assess the incidence, comorbidities, treatment modalities and mortality in
patients with necrotising soft-tissue infections (NSTIs) in Denmark. Design Nationwide …

Background Necrotizing soft tissue infections (NSTI) require immediate radical debridement,
broad-spectrum antibiotics and intensive care. Hyperbaric oxygen therapy (HBOT) may be …

Abstract Introduction: Necrotizing Soft Tissue Infections (NSTI) are severe infections with
high mortality affecting a heterogeneous patient population. There is a need for a clinical …