Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Neuroinflammation is an inflammatory response in the brain and spinal cord, which can
involve the activation of microglia and astrocytes. It is a common feature of many central …

Inflammation plays a significant role in many disease processes. Development in molecular
imaging in recent years provides new insight into the diagnosis and treatment evaluation of …

The inducible expression of the mitochondrial translocator protein 18 kDa (TSPO) by
activated microglia is a prominent, regular feature of acute and chronic-progressive brain …

Importance Neuroinflammation may play a role in epilepsy. Translocator protein 18 kDa
(TSPO), a biomarker of neuroinflammation, is overexpressed on activated microglia and …

A biomarker that will enable the identification of patients at high-risk for developing post-
injury epilepsy is critically required. Microvascular pathology and related blood–brain barrier …

Epilepsy is a common chronic consequence of traumatic brain injury (TBI), contributing to
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …

Background: The lack of treatments which can prevent epilepsy development or improve
disease prognosis represents an unmet and urgent clinical need. The development of such …

Over the past decade a neurodevelopmental animal model with high validity for
schizophrenia has been developed based on the environmental risk factor known as …

Macrophages are key players in the pathogenesis of large-vessel vasculitis (LVV) and may
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …