Immune checkpoint inhibitor–induced myocarditis with myositis/myasthenia gravis overlap syndrome: a systematic review of cases

R Pathak, A Katel, E Massarelli, VM Villaflor… - The …, 2021 - academic.oup.com
Background The development of immune checkpoint inhibitors (ICIs) represents a paradigm
shift in the treatment of cancers. Despite showing remarkable efficacy, these agents can be …

Drugs that induce or cause deterioration of myasthenia gravis: an update

S Sheikh, U Alvi, B Soliven, K Rezania - Journal of Clinical Medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder which is characterized
by presence of antibodies against acetylcholine receptors (AChRs) or other proteins of the …

Incidence and distinct features of immune checkpoint inhibitor-related myositis from idiopathic inflammatory myositis: a single-center experience with systematic …

N Hamada, A Maeda, K Takase-Minegishi… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitor (ICI)-related myositis is a rare, potentially fatal condition that
warrants further studies. Its incidence, clinical features, and prognosis remain poorly …

Immune checkpoint inhibitors-related myocarditis: a review of reported clinical cases

L Zotova - Diagnostics, 2023 - mdpi.com
Myocarditis associated with the use of immune checkpoint inhibitors (ICI) is a rare
manifestation of their cardiotoxicity, but is characterized by a high mortality rate. A literature …

[HTML][HTML] Pathophysiology, diagnosis and management of cardiac toxicity induced by immune checkpoint inhibitors and BRAF and MEK inhibitors

D Arangalage, N Degrauwe, O Michielin… - Cancer treatment …, 2021 - Elsevier
Immune checkpoint inhibitors (ICIs) and BRAF and MEK inhibitors (BRAFi/MEKi) have
drastically improved the outcome of melanoma patients. ICIs can induce myocarditis, a rare …

TNF-α inhibitors and other biologic agents for the treatment of immune checkpoint inhibitor-induced myocarditis

X Liu, W Wu, L Fang, Y Liu, W Chen - Frontiers in Immunology, 2022 - frontiersin.org
With anti-PD-1 antibodies serving as a representative drug, immune checkpoint inhibitors
(ICIs) have become the main drugs used to treat many advanced malignant tumors …

Molecular pathways and cellular subsets associated with adverse clinical outcomes in overlapping immune-related myocarditis and myositis

BA Siddiqui, NL Palaskas, S Basu, Y Dai… - Cancer Immunology …, 2024 - aacrjournals.org
Immune checkpoint therapies (ICT) can induce life-threatening immune-related adverse
events, including myocarditis and myositis, which are rare but often concurrent. The …

Case Report: Treatment for steroid-refractory immune-related myocarditis with tofacitinib

Q Xing, Z Zhang, B Zhu, Q Lin, L Shen, F Li… - Frontiers in …, 2022 - frontiersin.org
Introduction Immune therapy has ushered in a new era of tumor treatment, at the expense of
immune-related adverse events, including rare but fatal adverse cardiovascular events, such …

Immune interactions in pembrolizumab (PD-1 inhibitor) cancer therapy and cardiovascular complications

A Banerjee, CA Narasimhulu… - American Journal of …, 2023 - journals.physiology.org
The use of immunotherapies like pembrolizumab (PEM) is increasingly common for the
management of numerous cancer types. The use of PEM to bolster T-cell response against …

Immune checkpoint inhibitor induced myocarditis, myasthenia gravis, and myositis: A single‐center case series

J Longinow, M Zmaili, W Skoza, N Kondoleon… - Cancer …, 2023 - Wiley Online Library
Background Immune checkpoint inhibitors can result in overlap syndrome comprised of
myasthenia gravis, myositis and myocarditis. However, the mortality predictors have not …