Identification of transcription factors potentially involved in human adipogenesis in vitro
Background Increased adiposity in humans leads to obesity, which is a major risk factor for
cardiovascular disease, type 2 diabetes, and cancer. We previously conducted an extensive …
cardiovascular disease, type 2 diabetes, and cancer. We previously conducted an extensive …
Unlocking Prognostic Genes and Multi-Targeted Therapeutic Bioactives from Herbal Medicines to Combat Cancer-Associated Cachexia: A Transcriptomics and …
S Muthamil, P Muthuramalingam, HY Kim… - International Journal of …, 2023 - mdpi.com
Cachexia is a devastating fat tissue and muscle wasting syndrome associated with every
major chronic illness, including cancer, chronic obstructive pulmonary disease, kidney …
major chronic illness, including cancer, chronic obstructive pulmonary disease, kidney …
[HTML][HTML] The IL-33/ST2 Axis Affects Adipogenesis Through Regulating the TRAF6/RelA Pathway
S Cao, X Qin, C Li, L Zhang, S Ren, W Zhou… - International Journal of …, 2024 - mdpi.com
Understanding the regulatory mechanisms of adipogenesis is essential for preventing
obesity. Interleukin-33 (IL-33) has recently attracted increasing attention for its role in …
obesity. Interleukin-33 (IL-33) has recently attracted increasing attention for its role in …
Chronic rapamycin treatment improved metabolic phenotype but inhibited adipose tissue browning in high-fat diet-fed C57BL/6J mice
Y Wang, Z He, X Li - Biological and Pharmaceutical Bulletin, 2017 - jstage.jst.go.jp
Rapamycin (Rap) has been demonstrated to affect lipid metabolism through stimulating
lipolysis, inhibiting de novo lipogenesis and reducing adiposity. In the present study, we …
lipolysis, inhibiting de novo lipogenesis and reducing adiposity. In the present study, we …
Rapamycin attenuates palmitate-induced lipid aggregation by up-regulating sirt-1 signaling in AML12 hepatocytes
Y Wang, X Li, Z He, W Chen, J Lu - Die Pharmazie-An …, 2016 - ingentaconnect.com
Rapamycin (Rap), a specific inhibitor of the mTOR signaling, has been shown to affect lipid
metabolism in vitro and in vivo. Sirt-1, an NAD+ dependent deacetylase, regulates a variety …
metabolism in vitro and in vivo. Sirt-1, an NAD+ dependent deacetylase, regulates a variety …
Chronic rapamycin treatment exacerbates metabolism and does not down-regulate mTORC2/Akt signaling in diabetic mice induced by high-fat diet and streptozotocin
Y Wang, Z He, X Li, W Chen, J Lu… - Die Pharmazie-An …, 2015 - ingentaconnect.com
Rapamycin, a classical inhibitor of the mammalian target of rapamycin (mTOR), has been
intensively studied for its role in metabolism and verified to induce metabolic defects through …
intensively studied for its role in metabolism and verified to induce metabolic defects through …