The aim of this review was to consider the effects of induced hypocapnia both on systemic
physiology and on the physiology of the intracranial system. Hyperventilation lowers …

Anemia is frequent among brain-injured patients, where it has been associated with an
increased risk of poor outcome. The pathophysiology of anemia in this patient population …

Objective To investigate the relationship between oxygenation and short-term outcomes in
patients with traumatic brain injury (TBI). Design Logistic regression analysis was used to …

Introduction Anemia is one of the most common medical complications to be encountered in
critically ill patients. Based on the results of clinical trials, transfusion practices across the …

Despite suggestive data from microdialysis studies, direct measurement of the ability of the
brain to utilize oxygen indicates that hyperoxia does not increase oxygen utilization. This …

Traumatic brain injury is one of the most difficult and challenging management problems
facing clinicians. Research is increasingly clarifying the underlying physiological …

This article reviews cellular energy transformation processes and neurochemical events that
take place at the time of brain injury and shortly thereafter, emphasizing hypoxia-ischemia …

Energy metabolism of the brain is unique, possessing high aerobic metabolism with no
significant capacity for anaerobic glycolysis and limited tissue stores of glucose. A steady …

Levels of jugular blood oxygen saturation (SjvO 2) and lactate have been proposed as
indicators of cerebral ischemia and prognosis. However, sensitivity and specificity of these …

BACKGROUND: Elevated intracranial pressure (ICP) is significantly associated with high
mortality rate in severe head injury (SHI) patients. However, there is no absolute agreement …