Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
L Wang, C He - Frontiers in immunology, 2022 - frontiersin.org
Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …
main innate immune effector cells triggering the initial inflammatory responses in the …
NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease
A Boutten, D Goven, E Artaud-Macari… - Trends in molecular …, 2011 - cell.com
Several convergent destructive mechanisms such as oxidative stress, alveolar cell
apoptosis, extracellular matrix proteolysis and chronic inflammation contribute to chronic …
apoptosis, extracellular matrix proteolysis and chronic inflammation contribute to chronic …
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy
S Li, L Zheng, J Zhang, X Liu, Z Wu - Free Radical Biology and Medicine, 2021 - Elsevier
Diabetic nephropathy (DN) is now considered the leading cause of end-stage renal disease.
In diabetes, the accumulation of reactive oxygen species (ROS) and iron overload are …
In diabetes, the accumulation of reactive oxygen species (ROS) and iron overload are …
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway
QY Lu, LJ Yang, JJ Xiao, Q Liu, LH Ni, JW Hu… - Free Radical Biology …, 2023 - Elsevier
Renal tubular damage plays a key role in the pathogenesis of diabetic kidney disease
(DKD), and one of the main pathological process associated with DKD in diabetic mice is the …
(DKD), and one of the main pathological process associated with DKD in diabetic mice is the …
Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle
B Aravamudan, A Kiel, M Freeman… - … of Physiology-Lung …, 2014 - journals.physiology.org
The balance between mitochondrial fission and fusion is crucial for mitochondria to perform
its normal cellular functions. We hypothesized that cigarette smoke (CS) disrupts this …
its normal cellular functions. We hypothesized that cigarette smoke (CS) disrupts this …
Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction
I Hwang, J Lee, JY Huh, J Park, HB Lee, YS Ho… - Diabetes, 2012 - Am Diabetes Assoc
Mitochondrial reactive oxygen species (ROS) play an important role in diabetes
complications, including diabetic nephropathy (DN). Plasma free fatty acids (FFAs) as well …
complications, including diabetic nephropathy (DN). Plasma free fatty acids (FFAs) as well …
Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner
BF Peake, CK Nicholson, JP Lambert… - American Journal …, 2013 - journals.physiology.org
Hydrogen sulfide (H2S) therapy protects nondiabetic animals in various models of
myocardial injury, including acute myocardial infarction and heart failure. Here, we sought to …
myocardial injury, including acute myocardial infarction and heart failure. Here, we sought to …
Crocin attenuates cigarette smoke-induced lung injury and cardiac dysfunction by anti-oxidative effects: the role of Nrf2 antioxidant system in preventing oxidative …
Background Chronic obstructive pulmonary disease (COPD) has been emerging as a great
health problem in world. Cigarette smoke is known to cause oxidative stress and deplete …
health problem in world. Cigarette smoke is known to cause oxidative stress and deplete …
Nuclear factor erythroid 2-related factor 2 nuclear translocation induces myofibroblastic dedifferentiation in idiopathic pulmonary fibrosis
E Artaud-Macari, D Goven, S Brayer… - Antioxidants & redox …, 2013 - liebertpub.com
Aims: Oxidants have been implicated in the pathophysiology of idiopathic pulmonary fibrosis
(IPF), especially in myofibroblastic differentiation. We aimed at testing the hypothesis that …
(IPF), especially in myofibroblastic differentiation. We aimed at testing the hypothesis that …
E‐cigarette vapor induces an apoptotic response in human gingival epithelial cells through the caspase‐3 pathway
M Rouabhia, HJ Park, A Semlali… - Journal of cellular …, 2017 - Wiley Online Library
Electronic cigarettes represent an increasingly significant proportion of today's consumable
tobacco products. E‐cigarettes contain several chemicals which may promote oral diseases …
tobacco products. E‐cigarettes contain several chemicals which may promote oral diseases …