Neutralizing antibodies (nAbs) are being increasingly used as passive antiviral reagents in
prophylactic and therapeutic modalities and to guide viral vaccine design. In vivo, nAbs can …

Dengue, caused by four closely related viruses, is a growing global public health concern,
with outbreaks capable of overwhelming health-care systems and disrupting economies …

Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …

Following viral infection, viral antigens bind specifically to receptors on the surface of
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …

The flavivirus envelope glycoproteins prM and E drive the assembly of icosahedral, spiky
immature particles that bud across the membrane of the endoplasmic reticulum. Maturation …

Background African swine fever virus (ASFV) is the etiologic agent of African swine fever
(ASF), a disease of highly contagious and significant threat to pork production. At present …

Tick-borne encephalitis virus (TBEV) is a flavivirus that causes human neuroinfections and
represents a growing health problem. The human monoclonal antibody T025 targets …

Sequential dengue virus (DENV) infections often generate neutralizing antibodies against
all four DENV serotypes and sometimes, Zika virus. Characterizing cross-flavivirus broadly …

Neutralizing antibodies (NAbs) are naturally produced by our immune system to combat viral
infections. Clinically, neutralizing antibodies with potent efficacy and high specificity have …

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne
bunyavirus that causes severe fever with thrombocytopenia syndrome (SFTS), with a high …