Lung organoids: current uses and future promise
CE Barkauskas, MI Chung, B Fioret, X Gao… - …, 2017 - journals.biologists.com
Lungs are composed of a system of highly branched tubes that bring air into the alveoli,
where gas exchange takes place. The proximal and distal regions of the lung contain …
where gas exchange takes place. The proximal and distal regions of the lung contain …
CellRank for directed single-cell fate mapping
Computational trajectory inference enables the reconstruction of cell state dynamics from
single-cell RNA sequencing experiments. However, trajectory inference requires that the …
single-cell RNA sequencing experiments. However, trajectory inference requires that the …
Nasal mucus proteome and its involvement in allergic rhinitis
PV Tomazic, B Darnhofer… - Expert review of …, 2020 - Taylor & Francis
Introduction: Nasal mucus is the first line defense barrier against various pathogens
including allergens. Proteins in nasal mucus maybe used as biomarkers for diagnosis or …
including allergens. Proteins in nasal mucus maybe used as biomarkers for diagnosis or …
LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation
Q Liao, Z Zeng, X Guo, X Li, F Wei, W Zhang, P Chen… - Oncogene, 2014 - nature.com
Abstract Tumor-associated macrophage (TAM)-related chronic inflammation and interleukin-
6 (IL-6) contribute to the progression of nasopharyngeal carcinoma (NPC). In this study, we …
6 (IL-6) contribute to the progression of nasopharyngeal carcinoma (NPC). In this study, we …
Molecular evolution of the bactericidal/permeability-increasing protein (BPIFA1) regulating the innate immune responses in mammals
Bactericidal/permeability-increasing protein, a primary factor of the innate immune system of
mammals, participates in natural immune protection against invading bacteria. BPIFA1 …
mammals, participates in natural immune protection against invading bacteria. BPIFA1 …
On the saliva proteome of the Eastern European house mouse (Mus musculus musculus) focusing on sexual signalling and immunity
P Stopka, B Kuntová, P Klempt, L Havrdová… - Scientific Reports, 2016 - nature.com
Chemical communication is mediated by sex-biased signals abundantly present in the urine,
saliva and tears. Because most studies concentrated on the urinary signals, we aimed to …
saliva and tears. Because most studies concentrated on the urinary signals, we aimed to …
[HTML][HTML] Molecular biology of BPIFB1 and its advances in disease
J Li, P Xu, L Wang, M Feng, D Chen… - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
Abstract Bactericidal/permeability-increasing (BPI)-fold-containing family B member 1
(BPIFB1), also known as long-palate lung and nasal epithelium clone 1 (LPLUNC1) …
(BPIFB1), also known as long-palate lung and nasal epithelium clone 1 (LPLUNC1) …
An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection
The airway epithelium secretes proteins that function in innate defense against infection.
Bactericidal/permeability-increasing fold-containing family member A1 (BPIFA1) is secreted …
Bactericidal/permeability-increasing fold-containing family member A1 (BPIFA1) is secreted …
An in vitro model of murine middle ear epithelium
Otitis media (OM), or middle ear inflammation, is the most common paediatric disease and
leads to significant morbidity. Although understanding of underlying disease mechanisms is …
leads to significant morbidity. Although understanding of underlying disease mechanisms is …
Intense light-elicited alveolar type 2-specific circadian PER2 protects from bacterial lung injury via BPIFB1
Y Oyama, SR Shuff, N Burns… - American Journal of …, 2022 - journals.physiology.org
Circadian amplitude enhancement has the potential to be organ protective but has not been
studied in acute lung injury (ALI). Consistent light and dark cycles are crucial for the …
studied in acute lung injury (ALI). Consistent light and dark cycles are crucial for the …