Obesity has tripled over the past 40 years to become a major public health issue, as it is
linked with increased mortality and elevated risk for various physical and neuropsychiatric …

Ever since the brain was identified as an insulin-sensitive organ, evidence has rapidly
accumulated that insulin action in the brain produces multiple behavioral and metabolic …

Fat mass and obesity-associated gene (FTO) is a member of the Fe (II)-and oxoglutarate-
dependent AlkB dioxygenase family and is linked to both obesity and intellectual disability …

The specific eating pattern of Binge Eating Disorder (BED) patients has provoked the
assumption that BED might represent a phenotype within the obesity spectrum that is …

Epitranscriptomics, also known as “RNA epigenetics”, is a chemical modification for RNA
regulation. Ribonucleic acid (RNA) methylation is considered to be a major discovery …

Obesity is a major public health concern that involves an interaction between genetic
susceptibility and exposure to environmental cues (eg, food marketing); however, the …

Background Variants in the first intron of the fat mass and obesity-associated (FTO) gene
increase obesity risk. People with “high-risk” FTO genotypes exhibit preference for high-fat …

The use of neuroimaging tools, especially functional magnetic resonance imaging, in
nutritional research has increased substantially over the past 2 decades. Neuroimaging is a …

Modern food environments are conducive to overeating and weight gain, but not everyone
develops obesity. One reason for this may be that individuals differ in appetitive …

This review examines the biology of the Fat mass-and obesity-associated gene (FTO), and
the implications of genetic association of FTO SNPs with obesity and genetic aging. Notably …