Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to
public health by causing severe and invasive (mostly nosocomial) infections linked with high …

Increasing antibiotic resistance in multidrug-resistant (MDR) Gram-negative bacteria (MDR-
GNB) presents significant health problems worldwide, since the vital available and effective …

Colistin regained global interest as a consequence of the rising prevalence of multidrug-
resistant Gram-negative Enterobacteriaceae. In parallel, colistin-resistant bacteria emerged …

Being a multidrug-resistant and an invasive pathogen, Acinetobacter baumannii is one of
the major causes of nosocomial infections in the current healthcare system. It has been …

Polymyxins are polycationic antimicrobial peptides that are currently the last-resort
antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections. The …

Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide
spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the …

Polymyxins have recently been re-introduced into the therapeutic arsenal to combat
infections caused by multidrug-resistant Gram-negative bacteria. However, the emergence …

Acinetobacter baumannii is an opportunistic pathogen of increasing importance due to its
propensity for intractable multidrug-resistant infections in hospitals. All clinical isolates …

Treating multidrug-resistant infections has increasingly relied on last-resort antibiotics,
including polymyxins, for example colistin. As polymyxins are given routinely, the prevalence …

Antibiotic resistance among pathogenic bacteria is an ever-increasing issue worldwide.
Unfortunately, very little has been achieved in the pharmaceutical industry to combat this …