Knotting matters: orderly molecular entanglements

Z Ashbridge, SDP Fielden, DA Leigh, L Pirvu… - Chemical Society …, 2022 - pubs.rsc.org
Entangling strands in a well-ordered manner can produce useful effects, from shoelaces and
fishing nets to brown paper packages tied up with strings. At the nanoscale, non-crystalline …

[HTML][HTML] Artificial molecular machines

S Erbas-Cakmak, DA Leigh, CT McTernan… - Chemical …, 2015 - ACS Publications
The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

[HTML][HTML] Emerging applications of carbon nanohoops

EJ Leonhardt, R Jasti - Nature Reviews Chemistry, 2019 - nature.com
A cycloparaphenylene can be thought of as the shortest possible cross section of an
armchair carbon nanotube. Although envisioned decades ago, these molecules—also …

[HTML][HTML] Controlling catalyst activity, chemoselectivity and stereoselectivity with the mechanical bond

AW Heard, JM Suárez, SM Goldup - Nature Reviews Chemistry, 2022 - nature.com
Mechanically interlocked molecules, such as rotaxanes and catenanes, are receiving
increased attention as scaffolds for the development of new catalysts, driven by both their …

Development of pseudorotaxanes and rotaxanes: from synthesis to stimuli-responsive motions to applications

M Xue, Y Yang, X Chi, X Yan, F Huang - Chemical reviews, 2015 - ACS Publications
The history of isomeric types of organic molecules has passed through several important
stages:(1) Molecules that differ from each other with different numbers and types of atoms;(2) …

Catenanes: fifty years of molecular links

G Gil‐Ramírez, DA Leigh… - Angewandte Chemie …, 2015 - Wiley Online Library
Half a century after Schill and Lüttringhaus carried out the first directed synthesis of a [2]
catenane, a plethora of strategies now exist for the construction of molecular Hopf links …

[HTML][HTML] Active template strategy for the preparation of π-conjugated interlocked nanocarbons

JH May, JM Van Raden, RL Maust, LN Zakharov… - Nature Chemistry, 2023 - nature.com
Mechanically interlocked carbon nanostructures represent a relatively unexplored frontier in
carbon nanoscience due to the difficulty in preparing these unusual topological materials …

Chirality in rotaxanes and catenanes

EMG Jamieson, F Modicom, SM Goldup - Chemical Society Reviews, 2018 - pubs.rsc.org
Although chiral mechanically interlocked molecules (MIMs) have been synthesised and
studied, enantiopure examples are relatively under-represented in the pantheon of reported …

Click chemistry: 1, 2, 3‐triazoles as pharmacophores

SG Agalave, SR Maujan… - Chemistry–An Asian …, 2011 - Wiley Online Library
Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …

Molecular knots

SDP Fielden, DA Leigh… - Angewandte Chemie …, 2017 - Wiley Online Library
The first synthetic molecular trefoil knot was prepared in the late 1980s. However, it is only in
the last few years that more complex small‐molecule knot topologies have been realized …