Many developments have occurred since the publication of the widely-used 2009 Canadian
Cardiovascular Society (CCS) Dyslipidemia guidelines. Here, we present an updated …

Objectives: This study sought to review the literature for risk prediction models in patients
with heart failure and to identify the most consistently reported independent predictors of risk …

Background Randomised controlled trials are considered the gold standard for testing the
efficacy of novel therapeutic interventions, and typically report the average treatment effect …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …

The assessment of risk has been a key element in efforts to define risk factors for
cardiovascular disease (CVD), to identify novel markers of risk for CVD, to identify and …

Objective To develop a clinical risk prediction tool for estimating the cumulative six month
risk of death and death or myocardial infarction to facilitate triage and management of …

Background The current paradigm for cardiovascular disease (CVD) emphasises absolute
risk assessment to guide treatment decisions in primary prevention. Although the derivation …

These guidelines update previous reports by working parties of the British Hypertension
Society in 19891 and 1993. 2 Since the 1993 guidelines much new evidence has emerged …

OBJECTIVE To determine the cardiovascular and coronary risk thresholds at which aspirin
for primary prevention of coronary heart disease is safe and worthwhile. DESIGN Meta …

Clinicians often have to make treatment decisions based on the likelihood that an individual
patient will benefit. In this article we consider the relevance of relative and absolute risk …