Clinical utility of EEG in diagnosing and monitoring epilepsy in adults
WO Tatum, G Rubboli, PW Kaplan, SM Mirsatari… - Clinical …, 2018 - Elsevier
Electroencephalography (EEG) remains an essential diagnostic tool for people with epilepsy
(PWE). The International Federation of Clinical Neurophysiology produces new guidelines …
(PWE). The International Federation of Clinical Neurophysiology produces new guidelines …
Large scale brain models of epilepsy: dynamics meets connectomics
MP Richardson - Journal of Neurology, Neurosurgery & Psychiatry, 2012 - jnnp.bmj.com
The brain is in a constant state of dynamic change, for example switching between cognitive
and behavioural tasks, and between wakefulness and sleep. The brains of people with …
and behavioural tasks, and between wakefulness and sleep. The brains of people with …
Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression
Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations,
but associations between neurobiological mechanisms and macroscale connectomics …
but associations between neurobiological mechanisms and macroscale connectomics …
Altered functional–structural coupling of large-scale brain networks in idiopathic generalized epilepsy
The human brain is a large-scale integrated network in the functional and structural domain.
Graph theoretical analysis provides a novel framework for analysing such complex …
Graph theoretical analysis provides a novel framework for analysing such complex …
Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study
Epilepsy is increasingly conceptualized as a network disorder. In this cross-sectional mega-
analysis, we integrated neuroimaging and connectome analysis to identify network …
analysis, we integrated neuroimaging and connectome analysis to identify network …
Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain
Our objective was to evaluate the brain regions showing increased and decreased
metabolism in patients at the time of generalized bursts of epileptic discharges in order to …
metabolism in patients at the time of generalized bursts of epileptic discharges in order to …
[HTML][HTML] Molecular targets for antiepileptic drug development
BS Meldrum, MA Rogawski - Neurotherapeutics, 2007 - Elsevier
This review considers how recent advances in the physiology of ion channels and other
potential molecular targets, in conjunction with new information on the genetics of idiopathic …
potential molecular targets, in conjunction with new information on the genetics of idiopathic …
Cellular and network mechanisms of spike‐wave seizures
H Blumenfeld - Epilepsia, 2005 - Wiley Online Library
Spike‐wave seizures are often considered a relatively “pure” form of epilepsy, with a uniform
defect present in all patients and involvement of the whole brain homogenously. Here, we …
defect present in all patients and involvement of the whole brain homogenously. Here, we …
[HTML][HTML] Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks
SG Hormuzdi, MA Filippov, G Mitropoulou… - … et Biophysica Acta (BBA …, 2004 - Elsevier
Gap junctions consist of intercellular channels dedicated to providing a direct pathway for
ionic and biochemical communication between contacting cells. After an initial burst of …
ionic and biochemical communication between contacting cells. After an initial burst of …
Clinical characteristics, risk factors, and outcomes associated with neonatal hemorrhagic stroke: a population-based case-control study
Importance Hemorrhage into the brain of term newborns often results in major injury and
lifelong disability. The clinical epidemiology of neonatal hemorrhagic stroke (NHS) remains …
lifelong disability. The clinical epidemiology of neonatal hemorrhagic stroke (NHS) remains …