RNA structures in alternative splicing and back‐splicing

B Xu, Y Meng, Y Jin - Wiley Interdisciplinary Reviews: RNA, 2021 - Wiley Online Library
Alternative splicing greatly expands the transcriptomic and proteomic diversities related to
physiological and developmental processes in higher eukaryotes. Splicing of long …

[HTML][HTML] Research progress on the composition and function of parasite-derived exosomes

M Nawaz, MI Malik, M Hameed, J Zhou - Acta tropica, 2019 - Elsevier
Parasites use excretory-secretory pathways to communicate with the host. Characterization
of exosomes within the excretory-secretory products reveal by which parasites manipulate …

Induction of virulence factors in Giardia duodenalis independent of host attachment

SJ Emery, M Mirzaei, D Vuong, D Pascovici… - Scientific reports, 2016 - nature.com
Giardia duodenalis is responsible for the majority of parasitic gastroenteritis in humans
worldwide. Host-parasite interaction models in vitro provide insights into disease and …

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates

J Ankarklev, O Franzén, D Peirasmaki… - BMC genomics, 2015 - Springer
Background The diarrhea-causing protozoan Giardia intestinalis makes up a species
complex of eight different assemblages (AH), where assemblage A and B infect humans …

Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis

SJ Emery, L Baker, BRE Ansell, M Mirzaei… - …, 2018 - academic.oup.com
Abstract Background Metronidazole (Mtz) is the frontline drug treatment for multiple
anaerobic pathogens, including the gastrointestinal protist, Giardia duodenalis. However …

Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNA-Seq

O Franzén, J Jerlström-Hultqvist… - PLoS computational …, 2013 - journals.plos.org
Giardia intestinalis is a common cause of diarrheal disease and it consists of eight
genetically distinct genotypes or assemblages (AH). Only assemblages A and B infect …

[HTML][HTML] Heat shock protein 90 from neglected protozoan parasites

N Roy, RK Nageshan, S Ranade, U Tatu - Biochimica et Biophysica Acta …, 2012 - Elsevier
Significant advances have been made in our understanding of heat shock protein 90
(Hsp90) in terms of its structure, biochemical characteristics, post-translational modifications …

Hsp90 inhibitors as new leads to target parasitic diarrheal diseases

A Debnath, D Shahinas, C Bryant, K Hirata… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Entamoeba histolytica and Giardia lamblia are anaerobic protozoan parasites that cause
amebiasis and giardiasis, two of the most common diarrheal diseases worldwide. Current …

Patterns of conservation of spliceosomal intron structures and spliceosome divergence in representatives of the diplomonad and parabasalid lineages

AJ Hudson, DC McWatters, BA Bowser… - BMC evolutionary …, 2019 - Springer
Background Two spliceosomal intron types co-exist in eukaryotic precursor mRNAs and are
excised by distinct U2-dependent and U12-dependent spliceosomes. In the diplomonad …

Mining the Giardia genome and proteome for conserved and unique basal body proteins

T Lauwaet, AJ Smith, DS Reiner, EP Romijn… - International journal for …, 2011 - Elsevier
Giardia lamblia is a flagellated protozoan parasite and a major cause of diarrhoea in
humans. Its microtubular cytoskeleton mediates trophozoite motility, attachment and …