How human papillomavirus replication and immune evasion strategies take advantage of the host DNA damage repair machinery
V Bordignon, EG Di Domenico, E Trento, G D'Agosto… - Viruses, 2017 - mdpi.com
The DNA damage response (DDR) is a complex signalling network activated when DNA is
altered by intrinsic or extrinsic agents. DDR plays important roles in genome stability and …
altered by intrinsic or extrinsic agents. DDR plays important roles in genome stability and …
Impairment of T cell function in parasitic infections
V Rodrigues, A Cordeiro-da-Silva… - PLoS neglected …, 2014 - journals.plos.org
In mammals subverted as hosts by protozoan parasites, the latter and/or the agonists they
release are detected and processed by sensors displayed by many distinct immune cell …
release are detected and processed by sensors displayed by many distinct immune cell …
[HTML][HTML] Transcriptional switch of hepatocytes initiates macrophage recruitment and T-cell suppression in endotoxemia
X Sun, J Wu, L Liu, Y Chen, Y Tang, S Liu, H Chen… - Journal of …, 2022 - Elsevier
Background & Aims The liver plays crucial roles in the regulation of immune defense during
acute systemic infections. However, the roles of liver cellular clusters and intercellular …
acute systemic infections. However, the roles of liver cellular clusters and intercellular …
The roles of programmed cell death ligand-1/programmed cell death-1 (PD-L1/PD-1) in HPV-induced cervical cancer and potential for their use in blockade therapy
L Zhang, Y Zhao, Q Tu, X Xue, X Zhu… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Cervical cancer induced by infection with human papillomavirus (HPV)
remains a leading cause of mortality for women worldwide although preventive vaccines …
remains a leading cause of mortality for women worldwide although preventive vaccines …
Extracellular vesicles mediated proinflammatory macrophage phenotype induced by radiotherapy in cervical cancer
J Ren, L Li, B Yu, E Xu, N Sun, X Li, Z Xing, X Han… - BMC cancer, 2022 - Springer
Background Radiotherapy is a highly effective treatment for cervical cancer. Recent studies
focused on the radiotherapy induced anti-tumor immunity. Whether tumor-derived …
focused on the radiotherapy induced anti-tumor immunity. Whether tumor-derived …
PD-L1: Can it be a biomarker for the prognosis or a promising therapeutic target in cervical cancer?
R Wang, Y Zhang, F Shan - International Immunopharmacology, 2022 - Elsevier
Cervical cancer is one of the most common in the female genital tract and remains a leading
cause that threatens the health and lives of women worldwide, although preventive vaccines …
cause that threatens the health and lives of women worldwide, although preventive vaccines …
Targeting the programmed cell death-1 pathway in genitourinary tumors: current progress and future perspectives
SA Mann, A Lopez-Beltran, F Massari… - Current drug …, 2017 - ingentaconnect.com
Background: Immune checkpoint inhibitors have revolutionized the treatment of many
malignancies with over a dozen new United States Food and Drug Administration (FDA) …
malignancies with over a dozen new United States Food and Drug Administration (FDA) …
Cytokines of cervical mucosa and human papilloma virus infection of the cervix: a descriptive study
A Daniilidis, J Koutsos, Z Oikonomou, M Nasioutziki… - Acta cytologica, 2016 - karger.com
Objective: The production of cytokines by various cervical cells can be triggered by antigenic
stimuli, including human papilloma virus (HPV) infection. The aim of the present study was to …
stimuli, including human papilloma virus (HPV) infection. The aim of the present study was to …
Expression and clinical significance of programmed death ligand 1 in nasopharyngeal carcinoma
Y Qu, D Wang, L Yang, HY Liu… - Molecular and …, 2018 - spandidos-publications.com
Nasopharyngeal carcinoma (NPC) has the highest incidence of all types of head and neck
cancer in China. The present study aimed to investigate the association between the …
cancer in China. The present study aimed to investigate the association between the …
The safety and efficacy of a novel method for treatment of HSIL
J Zhao, H Feng, T Wang, X Pang, Y Zhou… - Archives of Gynecology …, 2021 - Springer
Purpose To investigate the efficacy and safety of Nr-CWS on treatment of cervical HSIL.
Method In this observational study, 16 patients were treated with Nr-CWS 1 time every 2 …
Method In this observational study, 16 patients were treated with Nr-CWS 1 time every 2 …