Hydrogen sulfide (H 2 S) releasing agents: chemistry and biological applications

Y Zhao, TD Biggs, M Xian - Chemical communications, 2014 - pubs.rsc.org
Hydrogen sulfide (H2S) is a newly recognized signaling molecule with very potent
cytoprotective actions. The fields of H2S physiology and pharmacology have been rapidly …

Small-molecule fluorescent probes for H2S detection: Advances and perspectives

H Li, Y Fang, J Yan, X Ren, C Zheng, B Wu… - TrAC Trends in …, 2021 - Elsevier
Since attributed to the involvement in important physiological and pathological processes,
hydrogen sulfide (H 2 S) is regarded as another gasotransmitter like nitric oxide (NO) and …

Highly Stable and Selective Sensing of Hydrogen Sulfide in Living Mouse Brain with NiN4 Single-Atom Catalyst-Based Galvanic Redox Potentiometry

C Pan, F Wu, J Mao, W Wu, G Zhao, W Ji… - Journal of the …, 2022 - ACS Publications
Hydrogen sulfide (H2S) is recognized as a gasotransmitter and multifunctional signaling
molecule in the central nervous system. Despite its essential neurofunctions, the chemical …

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of …

B Szczesny, K Módis, K Yanagi, C Coletta… - Nitric oxide, 2014 - Elsevier
The purpose of the current study was to investigate the effect of the recently synthesized
mitochondrially-targeted H 2 S donor, AP39 [(10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5yl) …

Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells

LA Montoya, MD Pluth - Chemical communications, 2012 - pubs.rsc.org
Hydrogen sulfide (H2S) is an important biological messenger but few biologically-
compatible methods are available for its detection. Here we report two bright fluorescent …

Sulfhydration mediates neuroprotective actions of parkin

MS Vandiver, BD Paul, R Xu… - Nature …, 2013 - nature.com
Increases in S-nitrosylation and inactivation of the neuroprotective ubiquitin E3 ligase,
parkin, in the brains of patients with Parkinson's disease are thought to be pathogenic and …

Antioxidant and cell‐signaling functions of hydrogen sulfide in the central nervous system

U Shefa, MS Kim, NY Jeong… - Oxidative medicine and …, 2018 - Wiley Online Library
Hydrogen sulfide (H2S), a toxic gaseous molecule, plays a physiological role in regulating
homeostasis and cell signaling. H2S is produced from cysteine by enzymes, such as …

Hydrogen sulfide in pharmacotherapy, beyond the hydrogen sulfide-donors

E Zaorska, L Tomasova, D Koszelewski, R Ostaszewski… - Biomolecules, 2020 - mdpi.com
Hydrogen sulfide (H2S) is one of the important biological mediators involved in
physiological and pathological processes in mammals. Recently developed H2S donors …

Hydrogen sulfide: a neuromodulator and neuroprotectant in the central nervous system

X Zhang, JS Bian - ACS chemical neuroscience, 2014 - ACS Publications
Hydrogen sulfide (H2S) used to be known as a toxic gas. However, in the last two decades,
accumulating evidence has revealed its role as a bioactive molecule in the biological …

Interaction of hydrogen sulfide with nitric oxide in the cardiovascular system

BV Nagpure, JS Bian - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Historically acknowledged as toxic gases, hydrogen sulfide (H2S) and nitric oxide (NO) are
now recognized as the predominant members of a new family of signaling molecules,“ …