The contribution of the right ventricle (RV) to cardiac output is negligible in normal resting
conditions when pressures in the pulmonary circulation are low. However, the RV becomes …

Background Some patients with COVID-19 who have recovered from the acute infection
after experiencing only mild symptoms continue to exhibit persistent exertional limitation that …

Right ventricular–pulmonary artery coupling (RV-PA coupling) refers to the relationship
between RV contractility and RV afterload. Normal RV-PA coupling is maintained only when …

Aims Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common
and associated with adverse outcomes in left heart disease (LHD). This study sought to …

Heart failure with preserved ejection fraction (HFpEF) patients have an increased ventilatory
demand. Whether their ventilatory capacity can meet this increased demand is unknown …

Heart failure with preserved ejection fraction (HFpEF) is a major healthcare problem that is
raising in prevalence. There has been a shift in HpEF management towards early diagnosis …

Right heart dysfunction and failure is the principal determinant of adverse outcomes in
patients with pulmonary arterial hypertension (PAH). In addition to right ventricular (RV) …

Right ventricular (RV) functional adaptation to afterload determines outcome in pulmonary
hypertension (PH). RV afterload is determined by the dynamic interaction between …

Heart failure with preserved ejection fraction (HFpEF) represents one of the greatest unmet
needs in modern cardiology given its diagnostic difficulty and limited therapeutic options …

Right heart (RH) failure carries a high rate of morbidity and mortality. Patients who present
with RH failure often exhibit complex aberrant cardio-pulmonary physiology with varying …