A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

RS Keri, MR Patil, SA Patil, S Budagumpi - European Journal of Medicinal …, 2015 - Elsevier
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

Thiazole: A promising heterocycle for the development of potent CNS active agents

CB Mishra, S Kumari, M Tiwari - European journal of medicinal chemistry, 2015 - Elsevier
Thiazole is a valuable scaffold in the field of medicinal chemistry and has accounted to
display a variety of biological activities. Thiazole and its derivatives have attracted …

A review on anticancer potentials of benzothiazole derivatives

N Pathak, E Rathi, N Kumar, SG Kini… - Mini reviews in …, 2020 - ingentaconnect.com
Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …

Structural relaxation enabled by internal vacancy available in a 24-atom gold cluster reinforces catalytic reactivity

X Cai, W Hu, S Xu, D Yang, M Chen… - Journal of the …, 2020 - ACS Publications
Unveiling the mystery of the contribution of nonsurface or noninterface sites in a catalyst to
its catalytic performance remains a great challenge because of the difficulty in capturing …

Biological aspects of emerging benzothiazoles: a short review

R Ali, N Siddiqui - Journal of chemistry, 2013 - Wiley Online Library
In recent years heterocyclic compounds analogues and derivatives have attracted wide
attention due to their useful biological and pharmacological properties. Benzothiazole is …

Recent developments of hydrazide/hydrazone derivatives and their analogs as anticonvulsant agents in animal models

V Angelova, V Karabeliov… - Drug development …, 2016 - Wiley Online Library
ABSTRACT Preclinical Research Epilepsy is a chronic devastating neurological disorder
characterized by synchronous interictal discharges. Treatment with antiepileptic drugs …

Synthesis, biological evaluation and docking studies of 1, 3, 4-oxadiazole fused benzothiazole derivatives for anticancer drugs

M Subramanyam, R Sreenivasulu… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Hetero atom containing compounds are well studied class of organic
compounds exhibits variety of properties and applications. Design and synthesis of new …

Benzothiazole: A versatile and multitargeted pharmacophore in the field of medicinal chemistry

S Agarwal, D Gandhi, P Kalal - Letters in Organic Chemistry, 2017 - ingentaconnect.com
Background: Heterocycles are the gold mines in medicinal chemistry. Most drugs used in
today's medicinal period possess a heterocyclic nucleus. One of the interesting …

Design synthesis and anti-proliferative activity of some new coumarin substituted hydrazide–hydrazone derivatives

N Duangdee, W Mahavorasirikul… - Journal of Chemical …, 2020 - Springer
A series of 21 coumarin hydrazide–hydrazone derivatives were designed, synthesized and
evaluated potential cytotoxicity effects at 25 μg/mL for 48 h against liver cancer (HepG2) cell …

New supramolecules of bis (acylhydrazones)-linked bisphenol sulfide for Alzheimer's: targeting cholinesterases by in vitro and in silico approaches

M Ibrahim, M Ali, SA Halim, A Latif, M Ahmad, S Ali… - RSC …, 2023 - pubs.rsc.org
In current research, two functional components, ie, hydrazone and bisphenol sulfide were
combined to get useful supramolecules in medicinal chemistry. Herein 25 new 4, 4 …