A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …
which are common and integral feature of a variety of natural products and pharmaceutical …
Thiazole: A promising heterocycle for the development of potent CNS active agents
Thiazole is a valuable scaffold in the field of medicinal chemistry and has accounted to
display a variety of biological activities. Thiazole and its derivatives have attracted …
display a variety of biological activities. Thiazole and its derivatives have attracted …
A review on anticancer potentials of benzothiazole derivatives
Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …
imparts a broad spectrum of biological activities to it. The significant and potent activity of …
Structural relaxation enabled by internal vacancy available in a 24-atom gold cluster reinforces catalytic reactivity
X Cai, W Hu, S Xu, D Yang, M Chen… - Journal of the …, 2020 - ACS Publications
Unveiling the mystery of the contribution of nonsurface or noninterface sites in a catalyst to
its catalytic performance remains a great challenge because of the difficulty in capturing …
its catalytic performance remains a great challenge because of the difficulty in capturing …
Biological aspects of emerging benzothiazoles: a short review
R Ali, N Siddiqui - Journal of chemistry, 2013 - Wiley Online Library
In recent years heterocyclic compounds analogues and derivatives have attracted wide
attention due to their useful biological and pharmacological properties. Benzothiazole is …
attention due to their useful biological and pharmacological properties. Benzothiazole is …
Recent developments of hydrazide/hydrazone derivatives and their analogs as anticonvulsant agents in animal models
V Angelova, V Karabeliov… - Drug development …, 2016 - Wiley Online Library
ABSTRACT Preclinical Research Epilepsy is a chronic devastating neurological disorder
characterized by synchronous interictal discharges. Treatment with antiepileptic drugs …
characterized by synchronous interictal discharges. Treatment with antiepileptic drugs …
Synthesis, biological evaluation and docking studies of 1, 3, 4-oxadiazole fused benzothiazole derivatives for anticancer drugs
M Subramanyam, R Sreenivasulu… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Hetero atom containing compounds are well studied class of organic
compounds exhibits variety of properties and applications. Design and synthesis of new …
compounds exhibits variety of properties and applications. Design and synthesis of new …
Benzothiazole: A versatile and multitargeted pharmacophore in the field of medicinal chemistry
S Agarwal, D Gandhi, P Kalal - Letters in Organic Chemistry, 2017 - ingentaconnect.com
Background: Heterocycles are the gold mines in medicinal chemistry. Most drugs used in
today's medicinal period possess a heterocyclic nucleus. One of the interesting …
today's medicinal period possess a heterocyclic nucleus. One of the interesting …
Design synthesis and anti-proliferative activity of some new coumarin substituted hydrazide–hydrazone derivatives
N Duangdee, W Mahavorasirikul… - Journal of Chemical …, 2020 - Springer
A series of 21 coumarin hydrazide–hydrazone derivatives were designed, synthesized and
evaluated potential cytotoxicity effects at 25 μg/mL for 48 h against liver cancer (HepG2) cell …
evaluated potential cytotoxicity effects at 25 μg/mL for 48 h against liver cancer (HepG2) cell …
New supramolecules of bis (acylhydrazones)-linked bisphenol sulfide for Alzheimer's: targeting cholinesterases by in vitro and in silico approaches
In current research, two functional components, ie, hydrazone and bisphenol sulfide were
combined to get useful supramolecules in medicinal chemistry. Herein 25 new 4, 4 …
combined to get useful supramolecules in medicinal chemistry. Herein 25 new 4, 4 …