Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay: Miniperspective
In any biomedical and chemical context, a truthful description of chemical constitution
requires coverage of both structure and purity. This qualification affects all drug molecules …
requires coverage of both structure and purity. This qualification affects all drug molecules …
Quantitative 1H NMR. Development and Potential of an Analytical Method: An Update
GF Pauli, T Godecke, BU Jaki… - Journal of natural …, 2012 - ACS Publications
Covering the literature from mid-2004 until the end of 2011, this review continues a previous
literature overview on quantitative 1H NMR (qHNMR) methodology and its applications in …
literature overview on quantitative 1H NMR (qHNMR) methodology and its applications in …
Quantitative NMR spectroscopy in pharmaceutical applications
U Holzgrabe - Progress in Nuclear Magnetic Resonance …, 2010 - Elsevier
1H and 13C NMR spectroscopy is routinely used for the elucidation of structures of newly
synthesized compounds, natural products and semi-synthesized compounds. The …
synthesized compounds, natural products and semi-synthesized compounds. The …
Research progress of NMR in natural product quantification
ZF Wang, YL You, FF Li, WR Kong, SQ Wang - Molecules, 2021 - mdpi.com
In the fields of medicine and health, traditional high-performance liquid chromatography or
UV-visible spectrophotometry is generally used for substance quantification. However, over …
UV-visible spectrophotometry is generally used for substance quantification. However, over …
Marine indole alkaloid diversity and bioactivity. What do we know and what are we missing?
DC Holland, AR Carroll - Natural Product Reports, 2023 - pubs.rsc.org
Covering: marine indole alkaloids (n= 2048) and their reported bioactivities up to the end of
2021 Despite increasing numbers of marine natural products (MNPs) reported each year …
2021 Despite increasing numbers of marine natural products (MNPs) reported each year …
HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case
JG Napolitano, DC Lankin, TN Graf… - The Journal of …, 2013 - ACS Publications
This study demonstrates how regio-and diastereo-isomers with near-identical NMR spectra
can be distinguished and unambiguously assigned using quantum mechanical driven 1H …
can be distinguished and unambiguously assigned using quantum mechanical driven 1H …
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases
In order to discover novel probes that may help in the investigation and control of infectious
diseases through a new mechanism of action, we have evaluated a library of phenol-based …
diseases through a new mechanism of action, we have evaluated a library of phenol-based …
Skyllamycins D and E, Non-Ribosomal Cyclic Depsipeptides from Lichen-Sourced Streptomyces anulatus
J Bracegirdle, P Hou, VV Nowak… - Journal of Natural …, 2021 - ACS Publications
The skyllamycins are a class of heavily modified, non-ribosomal peptides, first isolated from
Streptomyces sp. KY11784. A Streptomyces strain with potent antibiotic activity against …
Streptomyces sp. KY11784. A Streptomyces strain with potent antibiotic activity against …
Validation of a Generic Quantitative 1H NMR Method for Natural Products Analysis
T Gödecke, JG Napolitano… - Phytochemical …, 2013 - Wiley Online Library
Introduction Nuclear magnetic resonance (NMR) spectroscopy is increasingly employed in
the quantitative analysis and quality control (QC) of natural products (NP) including …
the quantitative analysis and quality control (QC) of natural products (NP) including …
Reference and normalization methods: Essential tools for the intercomparison of NMR spectra
This review aims at providing an analysis of the various available reference methods in
nuclear magnetic resonance, based on recent literature. This paper will provide a tool to …
nuclear magnetic resonance, based on recent literature. This paper will provide a tool to …