Advances in mass spectrometry imaging for spatial cancer metabolomics

X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

[HTML][HTML] Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma

VM Ravi, P Will, J Kueckelhaus, N Sun, K Joseph… - Cancer cell, 2022 - cell.com
Glioblastomas are malignant tumors of the central nervous system hallmarked by subclonal
diversity and dynamic adaptation amid developmental hierarchies. The source of dynamic …

Spatial metabolomics and imaging mass spectrometry in the age of artificial intelligence

T Alexandrov - Annual review of biomedical data science, 2020 - annualreviews.org
Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Visualization of metabolites and microbes at high spatial resolution using MALDI mass spectrometry imaging and in situ fluorescence labeling

P Bourceau, B Geier, V Suerdieck, T Bien… - Nature …, 2023 - nature.com
Label-free molecular imaging techniques such as matrix-assisted laser desorption ionization
mass spectrometry imaging (MALDI-MSI) enable the direct and simultaneous mapping of …

MSiReader v1. 0: evolving open-source mass spectrometry imaging software for targeted and untargeted analyses

MT Bokhart, M Nazari, KP Garrard… - Journal of The …, 2017 - ACS Publications
A major update to the mass spectrometry imaging (MSI) software MSiReader is presented,
offering a multitude of newly added features critical to MSI analyses. MSiReader is a free …

Spatial metabolomics of in situ host–microbe interactions at the micrometre scale

B Geier, EM Sogin, D Michellod, M Janda… - Nature …, 2020 - nature.com
Spatial metabolomics describes the location and chemistry of small molecules involved in
metabolic phenotypes, defence molecules and chemical interactions in natural communities …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Mass spectrometry imaging for clinical research–latest developments, applications, and current limitations

PM Vaysse, RMA Heeren, T Porta, B Balluff - Analyst, 2017 - pubs.rsc.org
Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

A new update of MALDI-TOF mass spectrometry in lipid research

KM Engel, P Prabutzki, J Leopold, A Nimptsch… - Progress in lipid …, 2022 - Elsevier
Matrix-assisted laser desorption and ionization (MALDI) mass spectrometry (MS) is an
indispensable tool in modern lipid research since it is fast, sensitive, tolerates sample …