Microbial production of oleochemicals from renewable feedstocks remains an attractive
route to produce high-energy density, liquid transportation fuels and high-value chemical …

G protein-coupled receptors (GPCRs) detect compounds on the cell surface and are the
starting point of a number of medically relevant signaling cascades. Indeed, over 30% of …

Alcohol-forming fatty acyl reductases (FARs) catalyze the reduction of thioesters to alcohols
and are key enzymes for microbial production of fatty alcohols. Many metabolic engineering …

Antibiotics are a key control mechanism for synthetic biology and microbiology. Resistance
genes are used to select desired cells and regulate bacterial populations, however their use …

Microbial metabolism is an attractive route for producing medium chain length fatty acids, eg,
octanoic acid, used in the oleochemical industry. One challenge to this strategy is the lack of …

Plant lipids have essential biological roles in plant development and stress responses
through their functions in cell membrane formation, energy storage and signalling …

Fatty acid biosynthesis (FAB) is an essential and highly conserved metabolic pathway. In
bacteria, this process is mediated by an elaborate network of protein• protein interactions …

Chemical biosensors are an increasingly ubiquitous part of our lives. Beyond enzyme-
coupled assays, recent synthetic biology advances now allow us to hijack more complex …

The dominant strategy for tailoring the chain-length distribution of free fatty acids (FFA)
synthesized by heterologous hosts is expression of a selective acyl-acyl carrier protein …

The β-oxidation pathway, normally involved in the catabolism of fatty acids, can be
functionally made to act as a fermentative, iterative, elongation pathway when driven by the …