Cohort profile update: Tehran cardiometabolic genetic study

MS Daneshpour, M Akbarzadeh, H Lanjanian… - European Journal of …, 2023 - Springer
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study
that conducts periodic follow-ups. TCGS has created a comprehensive database comprising …

miR-4432 targets FGFBP1 in human endothelial cells

R Avvisato, P Mone, SS Jankauskas, F Varzideh… - Biology, 2023 - mdpi.com
Simple Summary The inner layer of blood vessels is formed by endothelial cells. When
these cells do not work properly, several issues ensue in the human body. One of these …

The AGT epistasis pattern proposed a novel role for ZBED9 in regulating blood pressure: Tehran Cardiometabolic genetic study (TCGS)

M Akbarzadeh, P Riahi, G Kolifarhood, H Lanjanian… - Gene, 2022 - Elsevier
Introduction High blood pressure is widely regarded as the most important risk factor for
cardiovascular diseases. Epistasis analysis may provide additional insight into the genetic …

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses

L Zhang, W Zhang, L He, H Cui, Y Wang, X Wu, X Zhao… - BMC medicine, 2023 - Springer
Background Despite epidemiological evidence associating gallstone disease (GSD) with
cardiovascular disease (CVD), a dilemma remains on the role of cholecystectomy in …

[HTML][HTML] SOCS3 gene polymorphism and hypertension susceptibility in Chinese population: a two-center case-control study

D Kuang, L Dong, L Liu, M Zuo, Y Xie… - BioMed Research …, 2021 - pmc.ncbi.nlm.nih.gov
Endothelial inflammation and vascular damage are essential risk factors contributing to
hypertension. Suppressor of cytokine signaling 3 (SOCS3) is involved in the regulation of …

Hypertension risk prediction based on SNPS by machine learning models

SA Lajevardi, M Kargari, MS Daneshpour… - Current …, 2023 - ingentaconnect.com
Background: Hypertension is one of the most significant underlying ailments of
cardiovascular disease; hence, methods that can accurately reveal the risk of hypertension …

ABHD17C represses apoptosis and pyroptosis in hepatocellular carcinoma cells.

L WANG, J WANG, C SHI, WEI WANG, J WU - Biocell, 2024 - search.ebscohost.com
Background: Alpha/beta hydrolase domain-containing protein 17C (ABHD17C) is a
depalmitoylation enzyme that removes the S-palmitoylation of targeted proteins. The …

Cohort profile update: Tehran Cardiometabolic Genetic Study, a path toward precision medicine

MS Daneshpour, M Akbarzadeh, H Lanjanian… - 2022 - researchsquare.com
Abstract The Tehran Cardiometabolic Genetic Study (TCGS) is a large population-based
cohort study with periodic follow-ups, which created a comprehensive database of 20,367 …

A CNN deep learning model to improve SNP-based hypertension risk prediction accuracy

SA Lajevardi, M Kargari, MS Daneshpour… - 2022 - researchsquare.com
Hypertension is a modifiable factor for cardiovascular diseases such as ischemic heart
disease, one of the leading causes of death worldwide, known as the silent killer. Therefore …