Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

[HTML][HTML] Prospects and challenges of dynamic DNA nanostructures in biomedical applications

T Tian, Y Li, Y Lin - Bone Research, 2022 - nature.com
The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

Sharp Switching of DNAzyme Activity through the Formation of a CuII‐Mediated Carboxyimidazole Base Pair

Y Takezawa, L Hu, T Nakama… - Angewandte Chemie …, 2020 - Wiley Online Library
DNAzymes are widely used as functional units for creating DNA‐based sensors and
devices. Switching of DNAzyme activity by external stimuli is of increasing interest. Herein …

Triplet Excimer Formation in a DNA Duplex with Silver Ion-Mediated Base Pairs

L Martínez-Fernández, FR Kohl, Y Zhang… - Journal of the …, 2024 - ACS Publications
The dynamics of excited electronic states in self-assembled structures formed between silver
(I) ions and cytosine-containing DNA strands or monomeric cytosine derivatives were …

Beyond nature's base pairs: machine learning-enabled design of DNA-stabilized silver nanoclusters

P Mastracco, SM Copp - Chemical Communications, 2023 - pubs.rsc.org
Sequence-encoded biomolecules such as DNA and peptides are powerful programmable
building blocks for nanomaterials. This paradigm is enabled by decades of prior research …

A Novel AgI‐DNA Rod Comprising a One‐Dimensional Array of 11 Silver Ions within a Double Helical Structure

T Atsugi, A Ono, M Tasaka, N Eguchi… - Angewandte Chemie …, 2022 - Wiley Online Library
DNA/RNA duplexes containing metal‐ion‐mediated base pairs (metallo‐base pairs) have
potential applications in developing nucleic acid‐based nanodevices and genetic code …

External stimulation-controlled dynamic DNA devices for biosensing and biomedical applications

W Xu, F Hu, J Li, J Shang, X Liu, Y Zeng, Q Wu… - Science China …, 2023 - Springer
DNA devices that can recognize molecular inputs and transform them into functional outputs
in an autonomous manner have been actively pursued as versatile toolkits for controlled …

[HTML][HTML] Metal-dependent base pairing of bifacial iminodiacetic acid-modified uracil bases for switching DNA hybridization partner

K Mori, Y Takezawa, M Shionoya - Chemical Science, 2023 - pubs.rsc.org
Dynamic control of DNA assembly by external stimuli has received increasing attention in
recent years. Dynamic ligand exchange in metal complexes can be a central element in the …

Metal-dependent DNA base pairing of 5-carboxyuracil with Itself and all four canonical nucleobases

Y Takezawa, A Suzuki, M Nakaya… - Journal of the …, 2020 - ACS Publications
A 5-carboxyuracil (caU) nucleobase was found to pair not only with A (caU–A) by hydrogen
bonding but also with other DNA nucleobases by metal coordination bonding. Metal …

Cu II-mediated stabilisation of DNA duplexes bearing consecutive ethenoadenine lesions and its application to a metal-responsive DNAzyme

SC Rajasree, Y Takezawa, M Shionoya - Chemical Communications, 2023 - pubs.rsc.org
Metal-mediated nucleobase pairing can play a central role in the expression of metal-
responsive DNA functions. We report the CuII-mediated stabilisation of DNA duplexes …