The Yersinia pestis type III secretion system: expression, assembly and role in the evasion of host defenses

GV Plano, K Schesser - Immunologic research, 2013 - Springer
Yersinia pestis, the etiologic agent of plague, utilizes a type III secretion system (T3SS) to
subvert the defenses of its mammalian hosts. T3SSs are complex nanomachines that allow …

Concerted Actions of a Thermo-labile Regulator and a Unique Intergenic RNA Thermosensor Control Yersinia Virulence

K Böhme, R Steinmann, J Kortmann… - PLoS …, 2012 - journals.plos.org
Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including
the yop effector and the ysc type III secretion genes, is controlled by the transcriptional …

Role of the Hha/YmoA family of proteins in the thermoregulation of the expression of virulence factors

C Madrid, JM Nieto, A Juárez - International journal of medical …, 2001 - Elsevier
Virulent bacteria are able to sense temperature changes and respond by modifying the
expression of-among others-genes that code for virulence factors. The chromatin-associated …

The ATP‐dependent ClpXP and Lon proteases regulate expression of the Yersinia pestis type III secretion system via regulated proteolysis of YmoA, a small histone …

MW Jackson, E Silva‐Herzog… - Molecular …, 2004 - Wiley Online Library
The Yersinia pestis plasmid pCD1‐encoded type III secretion system (T3SS) is essential for
the pathogenicity of Y. pestis in mammalian hosts. T3SS‐associated genes are maximally …

Evidence for direct protein-protein interaction between members of the enterobacterial Hha/YmoA and H-NS families of proteins

JM Nieto, C Madrid, E Miquelay, JL Parra… - Journal of …, 2002 - Am Soc Microbiol
Escherichia coli nucleoid-associated H-NS protein interacts with the Hha protein, a member
of a new family of global modulators that also includes the YmoA protein from Yersinia …

Expression of the hemolysin operon in Escherichia coli is modulated by a nucleoid-protein complex that includes the proteins Hha and H-NS

JM Nieto, C Madrid, A Prenafeta, E Miquelay… - Molecular and General …, 2000 - Springer
Abstract The Escherichia coli protein Hha is a temperature-and osmolarity-dependent
modulator of the expression of the hemolysin operon. The Hha protein was purified and its …

Temperature- and H-NS-Dependent Regulation of a Plasmid-Encoded Virulence Operon Expressing Escherichia coli Hemolysin

C Madrid, JM Nieto, S Paytubi, M Falconi… - Journal of …, 2002 - Am Soc Microbiol
ABSTRACT Proteins H-NS and Hha form a nucleoprotein complex that modulates
expression of the thermoregulated hly operon of Escherichia coli. We have been able to …

Role of hha and ler in Transcriptional Regulation of the esp Operon of Enterohemorrhagic Escherichia coli O157:H7

VK Sharma, RL Zuerner - Journal of bacteriology, 2004 - Am Soc Microbiol
The locus of enterocyte effacement (LEE), which includes five major operons (LEE1 through
LEE4 and tir), enables enterohemorrhagic Escherichia coli (EHEC) O157: H7 to produce …

[HTML][HTML] The small protein YmoA controls the Csr system and adjusts expression of virulence-relevant traits of Yersinia pseudotuberculosis

K Böhme, AK Heroven, S Lobedann, Y Guo… - Frontiers in …, 2021 - frontiersin.org
Virulence gene expression of Yersinia pseudotuberculosis changes during the different
stages of infection and this is tightly controlled by environmental cues. In this study, we show …

A new class of proteins regulating gene expression in enterobacteria

AV Mikulskis, GR Cornetis - Molecular microbiology, 1994 - Wiley Online Library
YmoA and Hha are highly similar bacterial proteins downregulating gene expression In
Yersinia entero‐colitlca and Escherichia coli. respectively. The pheno‐type of ymoA mutants …