This review explores forms of respiratory and autonomic plasticity, and associated outcome
measures, that are initiated by exposure to intermittent hypoxia. The review focuses primarily …

Background The recent discovery that a combination of noradrenergic and antimuscarinic
drugs improved upper airway muscle function during sleep and reduced OSA severity has …

Rationale: Daily exposure to mild intermittent hypoxia (MIH) may elicit beneficial
cardiovascular outcomes. Objectives: To determine the effect of 15 days of MIH and in-home …

Key points Ventilatory long‐term facilitation (vLTF) refers to respiratory neuroplasticity that
develops following intermittent hypoxia in both healthy and clinical populations. A sustained …

Alzheimer's Disease (AD) is a disorder that worsens over time causing loss of memory and
decline of cognitive functions. Current methods for diagnosis consist of neuroimaging scans …

In a prospective, randomized, controlled crossover study, we explored the effects of acute
intermittent hypoxia and acute continuous hypoxia on patients with mild–moderate …

Brief exposure to repeated episodes of low inspired oxygen, or acute intermittent hypoxia
(AIH), is a promising therapeutic modality to improve motor function after chronic, incomplete …

Study objectives We aimed to assess ventilatory control in typically developing children with
and without obstructive sleep apnea (OSA). Methods Otherwise healthy children referred for …

Intermittent hypoxia (IH) is commonly associated with pathological conditions, particularly
obstructive sleep apnoea. However, IH is also increasingly used to enhance health and …

Purpose We determined if oxidative stress prior to sleep onset is correlated to loop gain (LG)
and the arousal threshold (AT) during non‐rapid eye movement (NREM) sleep. We also …