The role of peptide hormones in insect lipid metabolism

U Toprak - Frontiers in Physiology, 2020 - frontiersin.org
Lipids are the primary storage molecules and an essential source of energy in insects during
reproduction, prolonged periods of flight, starvation, and diapause. The coordination center …

Endocrine regulation of lifespan in insect diapause

C Hutfilz - Frontiers in Physiology, 2022 - frontiersin.org
Diapause is a physiological adaptation to conditions that are unfavorable for growth or
reproduction. During diapause, animals become long-lived, stress-resistant …

Germline proliferation trades off with lipid metabolism in Drosophila

MA Rodrigues, C Dauphin-Villemant, M Paris… - Evolution …, 2024 - academic.oup.com
Little is known about the metabolic basis of life-history trade-offs but lipid stores seem to play
a pivotal role. During reproduction, an energetically highly costly process, animals mobilize …

Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

LW Wat, ZS Chowdhury, JW Millington, P Biswas… - Elife, 2021 - elifesciences.org
Sex differences in whole-body fat storage exist in many species. For example, Drosophila
females store more fat than males. Yet, the mechanisms underlying this sex difference in fat …

Regulation of insulin and adipokinetic hormone/glucagon production in flies

M Ahmad, L He, N Perrimon - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Metabolic homeostasis is under strict regulation of humoral factors across various taxa. In
particular, insulin and glucagon, referred to in Drosophila as Drosophila insulin‐like …

Peptide hormones in the insect midgut

K Wu, S Li, J Wang, Y Ni, W Huang, Q Liu… - Frontiers in …, 2020 - frontiersin.org
Insects produce many peptide hormones that play important roles in regulating growth,
development, immunity, homeostasis, stress, and other processes to maintain normal life. As …

Ion transport peptide regulates energy intake, expenditure, and metabolic homeostasis in Drosophila

M Gáliková, P Klepsatel - Genetics, 2022 - academic.oup.com
In mammals, energy homeostasis is regulated by the antagonistic action of hormones insulin
and glucagon. However, in contrast to the highly conserved insulin, glucagon is absent in …

Dietary amino acids promote glucagon-like hormone release to generate global calcium waves in adipose tissues in Drosophila

M Ahmad, S Wu, S Luo, W Shi, X Guo, Y Cao… - Nature …, 2025 - nature.com
Propagation of intercellular calcium waves through tissues has been found to coordinate
different multicellular responses. Nevertheless, our understanding of how calcium waves …

[HTML][HTML] Lipidome remodeling in aging normal and genetically obese Drosophila males

HF Hofbauer, C Heier, AKS Saji, RP Kühnlein - Insect biochemistry and …, 2021 - Elsevier
Lipid homeostasis is essential for insects to maintain phospholipid (PL)-based membrane
integrity and to provide on-demand energy supply throughout life. Triacylglycerol (TAG) is …

Adipokinetic hormone (AKH), energy budget and their effect on feeding and gustatory processes of foraging honey bees

G de Brito Sanchez, A Expósito Muñoz, L Chen… - Scientific Reports, 2021 - nature.com
The adipokinetic hormone (AKH) of insects is considered an equivalent of the mammalian
hormone glucagon as it induces fast mobilization of carbohydrates and lipids from the fat …