Dopamine, immunity, and disease
B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …
regulating many processes including reward, movement, and cognition. Dopamine also …
Dopamine in Parkinson's disease
S Latif, M Jahangeer, DM Razia, M Ashiq, A Ghaffar… - Clinica chimica acta, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease caused by the death of neurons, ie,
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …
Dopamine: functions, signaling, and association with neurological diseases
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …
[HTML][HTML] Dopamine: The neuromodulator of long-term synaptic plasticity, reward and movement control
L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …
including motor control, modulation of affective and emotional states, reward mechanisms …
Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology
SJ Kaar, S Natesan, R Mccutcheon, OD Howes - Neuropharmacology, 2020 - Elsevier
Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …
disorders but are ineffective for some patients and associated with side-effects and …
[HTML][HTML] ONC201 and imipridones: Anti-cancer compounds with clinical efficacy
ONC201 was originally discovered as TNF-Related Apoptosis Inducing Ligand (TRAIL)-
inducing compound TIC10. ONC201 appears to act as a selective antagonist of the G …
inducing compound TIC10. ONC201 appears to act as a selective antagonist of the G …
Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease
SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …
functions in a variety of peripheral systems. Growing research has also shown that …
The regulation of PKA signaling in obesity and in the maintenance of metabolic health
E London, CA Stratakis - Pharmacology & therapeutics, 2022 - Elsevier
The cAMP-dependent protein kinase (PKA) system represents a primary cell-signaling
pathway throughout systems and across species. PKA facilitates the actions of hormones …
pathway throughout systems and across species. PKA facilitates the actions of hormones …
D4 dopamine receptor high-resolution structures enable the discovery of selective agonists
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every
neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our …
neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our …
[HTML][HTML] The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia
H Xu, F Yang - Translational psychiatry, 2022 - nature.com
Dopamine (DA) is a major monoamine neurotransmitter in the brain and has essential roles
in higher functions of the brain. Malfunctions of dopaminergic signaling have been …
in higher functions of the brain. Malfunctions of dopaminergic signaling have been …