Polymeric nanoparticles: Promising platform for drug delivery
M Khalid, HS El-Sawy - International journal of pharmaceutics, 2017 - Elsevier
Nano medicine had viewed countless breakthroughs in drug delivery implementations. The
main objective of nanotechnology application in delivering and carrying many promising …
main objective of nanotechnology application in delivering and carrying many promising …
Nanoparticles for oral delivery: Design, evaluation and state-of-the-art
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …
delivery and minimizing off-target side effects is often challenging. Formulation into …
Drug metabolites and their effects on the development of adverse reactions: Revisiting Lipinski's Rule of Five
CM Chagas, S Moss, L Alisaraie - International journal of pharmaceutics, 2018 - Elsevier
Many studies have shown that toxicities of anticancer drugs and their adverse effects are
related to their chemical structure and high molecular weight that may result in a number of …
related to their chemical structure and high molecular weight that may result in a number of …
Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
Evaluation of mesoporous silica nanoparticles for oral drug delivery–current status and perspective of MSNs drug carriers
J Florek, R Caillard, F Kleitz - Nanoscale, 2017 - pubs.rsc.org
The oral pathway is considered as the most common method for drug administration,
although many drugs, especially the highly pH-and/or enzymatic biodegradable peptide …
although many drugs, especially the highly pH-and/or enzymatic biodegradable peptide …
Absorption, distribution, metabolism, and excretion of nanocarriers in vivo and their influences
A Zhang, K Meng, Y Liu, Y Pan, W Qu, D Chen… - Advances in colloid and …, 2020 - Elsevier
As one of the most promising and effective delivery systems for targeted controlled-release
drugs, nanocarriers (NCs) have been widely studied. Although the development of …
drugs, nanocarriers (NCs) have been widely studied. Although the development of …
Optimization to development of chitosan decorated polycaprolactone nanoparticles for improved ocular delivery of dorzolamide: In vitro, ex vivo and toxicity …
MS Shahab, M Rizwanullah, S Alshehri… - International journal of …, 2020 - Elsevier
The present research work was designed to develop dorzolamide-loaded chitosan-coated
polycaprolactone nanoparticles (DRZ-CS-PCL-NPs) for improved ocular delivery. The …
polycaprolactone nanoparticles (DRZ-CS-PCL-NPs) for improved ocular delivery. The …
Nano-phytosome as a potential food-grade delivery system
B Ghanbarzadeh, A Babazadeh, H Hamishehkar - Food bioscience, 2016 - Elsevier
Flavonoids have many nutritional-therapeutic and preservative features. Therefore, the aim
of using them for fortifying food products could provide new horizon in developing new …
of using them for fortifying food products could provide new horizon in developing new …
Nanostructured lipid carriers for oral bioavailability enhancement of exemestane: formulation design, in vitro, ex vivo, and in vivo studies
Exemestane (EXE) is a novel oral steroidal aromatase inhibitor approved for the treatment of
breast cancer. However, its oral clinical application is limited because of low aqueous …
breast cancer. However, its oral clinical application is limited because of low aqueous …
Nano-phytosome: a developing platform for herbal anti-cancer agents in cancer therapy
A Babazadeh, M Zeinali, H Hamishehkar - Current drug targets, 2018 - ingentaconnect.com
Background: Cancer is one of the main causes of death in the world. It has not yet been
cured in an efficient manner and has remained a major challenge for current chemotherapy …
cured in an efficient manner and has remained a major challenge for current chemotherapy …