Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

Physical, Electrochemical, and Solvent Permeation Properties of Amphiphilic Conetwork Membranes Formed through Interlinking of Poly(vinylidene fluoride)-Graft …

Anuradha, A Das, S Pal, SK Jewrajka - Langmuir, 2022 - ACS Publications
We report the preparation of dense and porous amphiphilic conetwork (APCN) membranes
through the covalent interconnection of poly (vinylidene fluoride)-graft-poly [(2 …

Injectable amphiphilic hydrogel systems from the self-assembly of partially alkylated poly (2-dimethyl aminoethyl) methacrylate with inherent antimicrobial property …

A Kumar, A Biswas, SK Jewrajka - European Polymer Journal, 2022 - Elsevier
Inability to encapsulate hydrophobic guest molecules and excessive water swelling by an
injectable hydrogel system restrict its application in sustained delivery. Herein, we report the …

Fast-relaxing hydrogels with reversibly tunable mechanics for dynamic cancer cell culture

YY Khine, H Nguyen, F Afolabi, CC Lin - Biomaterials Advances, 2024 - Elsevier
The mechanics of the tumor microenvironment (TME) significantly impact disease
progression and the efficacy of anti-cancer therapeutics. While it is recognized that …

[PDF][PDF] Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics. Biomedicines 2022, 10, 2055

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - 2022 - pharmaexcipients.com
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …