The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition

B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2017 - Taylor & Francis
Objective: Biomarkers are defined as anatomical, biochemical or physiological traits that are
specific to certain disorders or syndromes. The objective of this paper is to summarise the …

Risk factors for depression and anxiety in healthcare workers deployed during the COVID-19 outbreak in China

J Chen, X Liu, D Wang, Y Jin, M He, Y Ma… - Social psychiatry and …, 2021 - Springer
Purpose This study was conducted to evaluate the status of depression and anxiety of
healthcare workers and to explore the risk factors during the outbreak of COVID-19 in China …

[HTML][HTML] An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo …

AL Lopresti, SJ Smith, H Malvi, R Kodgule - Medicine, 2019 - journals.lww.com
Background: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to
reduce stress and enhance wellbeing. The aim of this study was to investigate its anxiolytic …

Changes in college student anxiety and depression from pre-to during-COVID-19: Perceived stress, academic challenges, loneliness, and positive perceptions

M Haikalis, H Doucette, MK Meisel… - Emerging …, 2022 - journals.sagepub.com
The COVID-19 pandemic is a major stressor that has negatively impacted global mental
health. Many US college students faced an abrupt transition to remote learning in March …

Probiotics: Potential novel therapeutics for microbiota-gut-brain axis dysfunction across gender and lifespan

S Snigdha, K Ha, P Tsai, TG Dinan, JD Bartos… - Pharmacology & …, 2022 - Elsevier
Probiotics are live microorganisms, which when administered in adequate amounts, present
a health benefit for the host. While the beneficial effects of probiotics on gastrointestinal …

Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders

MA Schiele, K Domschke - Genes, Brain and Behavior, 2018 - Wiley Online Library
The pathogenesis of anxiety disorders is multifactorial, involving complex interactions
between biological factors, environmental influences and psychological mechanisms …

Cortisol response to stress: The role of expectancy and anticipatory stress regulation

MM Pulopulos, C Baeken, R De Raedt - Hormones and behavior, 2020 - Elsevier
An exacerbated physiological response to stress is associated with the development of
stress-related disorders (eg, depression and anxiety disorders). Recently, it has been …

The lasting impact of earlylife adversity on individuals and their descendants: Potential mechanisms and hope for intervention

CSM Cowan, BL Callaghan, JM Kan… - Genes, Brain and …, 2016 - Wiley Online Library
The adverse effects of earlylife stress are pervasive, with wellestablished mental and
physical health consequences for exposed individuals. The impact of early adverse …

Methyl donors, epigenetic alterations, and brain health: understanding the connection

RA Bekdash - International Journal of Molecular Sciences, 2023 - mdpi.com
Methyl donors such as choline, betaine, folic acid, methionine, and vitamins B6 and B12 are
critical players in the one-carbon metabolism and have neuroprotective functions. The one …